原发性腹膜后恶性肿瘤的外科治疗与预后分析

目的 探讨原发性腹膜后恶性肿瘤的外科治疗和预后.方法 回顾性分析中国医学科学院北京协和医学院肿瘤医院1996年1月至2007年12月外科治疗的191例原发性恶性腹膜后肿瘤的临床资料并进行分析,应用SPSS 13.0对随诊资料进行统计学比较.结果 191例原发性腹膜后恶性肿瘤中,临床症状主要表现为腹部肿块(122例、63.9%),腹痛(77例、40.3%),腹胀(48例、25.1%)等.术后病理脂肪肉瘤75例(39.3%).肿瘤完整切除142例,姑息性切除35例,剖腹探查肿瘤活检术14例.完整切除组、姑息性切除组和剖腹探查组的中位生存期分别为56、33、11个月,差异有统计学意义(P=0.00).结论 手术切除是腹膜后恶件肿瘤的有效治疗方法,积极的外科治疗、争取完整切除可以延长患者的生存期.对于复发患者,应争取再次手术切除.

Surgical treatment and prognosis of primary retroperitoneal malignant tumor

Objective To investigate the surgical treatment and prognosis of primary retroperitoneal malignant tumor. Methods A total of 191 patients with primary retroperitoneal malignant tumor treated from January 1996 to December 2007 at our hospital were retrospectively analyzed SPSS 13.0 was used to analyze the follow-up data. Results The clinical manifestations included abdominal mass 122(63.9%)], abdominal pajn77(40.3%)]and abdominal distension48(25.1%)]. Liposarcoma75(39.3%)]was more frequently encountered than other tumors. Among these patients, 142 underwent complete resection, 35 palliative resection and 14 exploratory operation. The median survival time of complete resection, palliative resection and exploratory operation were 56, 33 and 11 months respectively. The difference was of statistical significance. Conclusions Surgical resection is an effective therapeutic method for primary retroperitoneal malignant tumor. Complete resection prolongs the survival time and it is effective in control of recurrent tumors.