经鼻高流量氧疗治疗婴儿社区获得性肺炎的疗效分析

目的:对比分析经鼻高流量氧疗(high-flow nasal oxygen cannula,HFNC)与普通氧疗在婴儿社区获得性肺炎中的疗效。方法:选取采取HFNC治疗的社区获得性肺炎患儿133例作为HFNC治疗组,选取采取普通氧疗治疗的社区获得性肺炎患儿160例为普通治疗组,观察两组治疗前、治疗后2 h呼吸频率、心率、动脉血氧分压改善情况,并对两组患儿经鼻处气体温度、湿度情况及气管插管率进行比较。结果:治疗2 h后,HFNC组患儿呼吸频率、心率、动脉血氧分压的改善明显优于普通氧疗组,差异有统计学意义(均P<0.05);HFNC组患儿经鼻处气体温度、湿度,分别为31.9~33℃、湿度84%~96%,普通氧疗组为温度22~27.3℃,湿度48%~53%;HFNC组患儿气管插管率为12.78%,明显低于普通氧疗组(均P<0.05)。结论:与普通氧疗对比,HFNC能有效的改善PICU中社区获得性肺炎婴儿的呼吸频率、心率、动脉血氧分压,经鼻处气体温度、湿度更合理,且降低气管插管率,故应作为氧疗的首选。

Analysis on curative effect of high-flow nasal cannula for community-ac-quired pneumonia in infant

Objective:To investigated the curative effects of high-flow nasal oxygen cannula (HFNC) compared with conven-tional oxygen therapy (COT) in subjects with community-acquired pneumonia(CAP)in infant.Methods:133 children with community acquired pneumonia treated with HFNC as HFNC treatment group,and 160 children with community-acquired pneumonia treated with ordinary oxygen therapy were selected as the general treatment group.The improvement of respiratory rate,heart rate and arterial oxygen pressure of 2 h before and after treatment in two groups was observed,and the gas temperature,humidity through the nose and tracheal intubation rate of the two groups of children were compared.Results:2 h after treatment,the respiratory rate,heart rate and arterial oxy-gen partial pressure in the HFNC group were obviously better than those in the ordinary oxygen therapy group,the difference was statis-tically significant (P<0.05 ).In group HFNC,the gas temperature and humidity through the nasal were 31.9~33 C,84% ~96%, the temperature of the common oxygen therapy group was 22~27.3,the humidity was 48% ~53%,and the rate of tracheal intubation in the HFNC group was 12.78%,which was significantly lower than that in the ordinary oxygen therapy group (P<0.05).Conclu-sions:Compared with conventional oxygen therapy,HFNC can effectively improve the respiratory rate,heart rate and arterial oxygen par-tial pressure of infants with community-acquired pneumonia in PICU,and the gas temperature and humidity through the nasal are more reasonable,and reduce the rate of tracheal intubation,so it should be the first choice for oxygen therapy.