严重急性呼吸综合征病人血清酶类的变化特点

目的 :分析非典型肺炎病人和疑似非典型肺炎病人发病期血清天冬氨酸转氨酶 ( AST)、丙氨酸转氨酶( AL T)、谷氨酰转肽酶 ( GGT)和乳酸脱氢酶 ( L DH)的变化特点。方法 :按照全国临床检验操作规程中 AST、AL T、GGT和 L DH的操作方法——连续监测法进行。结果 :观察到 5 0 %～ 87.5 %非典型肺炎病人的 AST、AL T、GGT和 L DH轻度或中度升高。且确诊组检测结果比疑似组或健康人群高。经统计学处理 ,差别显著。这四种血清酶在非典型肺炎发病初期和高峰期升高 ,一般在 10 d内下降 ,恢复正常。结论 :非典型肺炎病人在发病期间会出现肝功能异常 ,且与病情有一定的相关性 ,提示医生在病程中应注意护肝治疗。

The Changing Features of Serum Aminotransferases in the Severe Acute Respiratory Syndrome Patient

Object To investigate the changing features of some serum aminotransferases AST、ALT、GGT and LDH of the severe acute respiratory syndrome patients and possible cases.Methods According to the national rules of operation on clinic labolatory tests.Results The values of AST、ALT、GGT and LDH from 50 %～87.5 % of SARS patients were higher than possible cases and normal persons.According to statistical analysis, the difference between the patient group and possible group or normal group was predominant.The four enzymes were elevated during earlier and serious period of SARS, which lowered down and converted into normal value within 10 days.Conclusion Hepatic dysfunction occured during the course of SARS, which correlated to patients condition.It prompted the doctor to pay attention to use hepatinica during the course of disease.