MR扩散加权成像对乳腺良恶性病变诊断价值

目的探讨MR扩散加权成像及表观扩散系数（ADC值）对乳腺良恶性病变的诊断价值。方法对77例女性乳腺患者行MRI—DWI（b=500、800s／mm2）检查，相同的感兴趣区（ROI）下，测量病变的ADC值，结果进行统计学分析，所有病变均经手术及病理证实。结果b值分别取5OO、800s／mm2，乳腺良恶性病变的ADC值差异均有统计学意义（t=7．027，P〈0．001；t=6．399，P〈0．001）；b-500s／mm2，最佳诊断点ADC值为1．13×10-3mm2／S ROC曲线下面积为0．90，灵敏度为90．7％，特异度为79．4％；b=800s／mm2，最佳诊断点ADC值为1．03×10-3mm2／S，ROC曲线下面积为0．88，灵敏度为81．4％，特异度为88．2％。结论MR扩散加权成像及ADC值对乳腺良恶性病变诊断有重要价值。

MR Diffusion-weighted Imaging Diagnostics Value of Benign and Malignant Breast Lesions

To evaluate the value of the diffusion-weighted imaging （DWI） and apparent diffusion coefficient （ADC） values in distinguishing benign from malignant breast lesions. Me, otis MRI-DWI （b=500, 800s/mm2） performed in fifty-three cases of female breast lesions. The apparent diffusion coefficients （ADC） of these lesions were measured for statistical analysis. All the lesions were confirmed by operation and pathology. b=500 and 800s/mm2, the benign and malignant breast lesions showed significant differences in ADC values （t=7.03, P〈0.001, t=6.40, P〈0.001）, b=500s/mm2, the best diagnostic ADC value of 1.13Xl0-3mm2/s, ROC area under the curve is 0.90, sensitivity to 90.7%, specificity of 79.4%, b=800, the best diagnostic ADC value of 1.03× 10-3mm2/s, ROC area under the curve was 0.88, and sensitivity to 81.4%, specificity of 88.2%. MR diffusion weighted imaging and ADC measurement has important value for the diagnosis of benign and malignant breast lesions.