| Regulative Actions of the Chinese Drugs for Tonifying the Kidney on Gene Expression of the Hypothalamic GnRH, Pituitary FSH, LH and Osteoblastic BGP |
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| 作者姓名： | 蔡德培 张炜 |
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| 作者单位： | [1]PediatricHospitalAffiliatedtoShanghaiMedicalUniversity,Shanghai200032,China [2]ShanghaiPasaikeBioengineeringInstitute,Shanghai200032,China |
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| 摘 要： | It is found that the drugs for nourishing yin to reduce pathogenic fire can significantly down-regulate, and the drugs for tonifying the kidney to replenish essence can up-regulate mRNA expression of the hypothalamic GnRH, pituitary FSH, LH and osteoblastic BGP, indicating that the Chinese drugs for tonifying the kidney can regulate gene expression of the hypothalamic GnRH, pituitary FSH, LH, and osteoblastic BGP, which is possibly one of the main mechanisms of the Chinese drug for tonifying the kidney, regulating ephebic development process and improving skeletal development in sexual precocity children.
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| 关 键 词： | 中医药疗法 基因表达 下丘脑 垂体 造骨细胞 小儿 性早熟 骨骼发育 |
Regulative Actions of the Chinese Drugs for Tonifying the Kidney on Gene Expression of the Hypothalamic GnRH, Pituitary FSH, LH and Osteoblastic BGP |
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| Depei Cai,Wei Zhang.Regulative Actions of the Chinese Drugs for Tonifying the Kidney on Gene Expression of the Hypothalamic GnRH, Pituitary FSH, LH and Osteoblastic BGP[J].Journal of Traditional Chinese Medicine,2005,25(1):58-61. |
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| Authors: | Depei Cai Wei Zhang |
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| Affiliation: | Pediatric Hospital Affiliated to Shanghai Medical University, Shanghai 200032, China. |
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| Abstract: | It is found that the drugs for nourishing yin to reduce pathogenic fire can significantly down-regulate, and the drags for tonifying the kidney to replenish essence can up-regulate mRNA expression of the hypothalamic GnRH, pituitary FSH, LH and osteoblastic BGP, indicating that the Chinese drugs for tonifying the kidney can regulate gene expression of the hypothalamic GnRH, pituitary FSH, LH, and osteoblastic BGP, which is possibly one of the main mechanisms of the Chinese drug for tonifying the kidney, regulating ephebic development process and improving skeletal development in sexual precocity children. |
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