| 喜之降胶囊调脂作用的实验研究 |
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| 引用本文： | 蒲晓东,尹涛.喜之降胶囊调脂作用的实验研究[J].重庆医科大学学报,2007,32(2):176-177,188. |
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| 作者姓名： | 蒲晓东 尹涛 |
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| 作者单位： | 重庆医科大学中医药学院经典理论教研室,重庆,400050 |
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| 摘 要： | 目的:为研究喜之降胶囊调节血脂的效果,观察了喜之降胶囊对高脂血症(HL)大鼠血清脂质和肝脏脂水平的影响.方法:实验根据大鼠体重、血脂水平进行随机分组,设正常对照组、高脂饲料对照组、喜之降胶囊低、中、高剂量组(分别为0.28、0.55、1.10g/(kg.bw)).受试物每天经口灌胃给予.4周末测定血清胆固醇(TC)、甘油三酯(TG)、高密度脂蛋白胆固醇(HDL-C),同时测定肝脏TC、TG.结果:喜之降胶囊各组与高脂饲料对照组比较,大鼠血清TC、TG水平降低,差异有显著性(P＜0.05),喜之降胶囊对高脂大鼠肝脏胆固醇、甘油三酯有显著的降低作用(P＜0.01).结论:喜之降胶囊有降低高脂大鼠血脂水平的作用.
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| 关 键 词： | 高脂血症 大鼠 喜之降胶囊 |
| 文章编号： | 0253-3626（2007）02-0176-02 |
| 修稿时间： | 2006-06-19 |
Experimental study on lipid regulation function of the Xi-zhi-jiang Capsule |
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| PU Xiaodong,et al.Experimental study on lipid regulation function of the Xi-zhi-jiang Capsule[J].Journal of Chongqing Medical University,2007,32(2):176-177,188. |
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| Authors: | PU Xiaodong |
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| Affiliation: | Department of Traditional Chinese Medicine, Chongqing Medical University |
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| Abstract: | Objective:To observe the effect of the Xi-zhi-jiang Capsule on serum and liver lipid levels of rats with hyperlipidemia to study the effects of Xi-zhi-jiang capsule on blood Lipid regulation.Methods:Male SD rats were randomly divided into five groups(normal control group,high lipid fed group and three Xi-zhi-jiang capsule groups,which were administrated Xi-zhi-jiang capsule of 0.28,0.55,1.10(g/(kg.bw))respectively.Four weeks later,bodyweight,the serum TC,TG,HDL-C and the liver TC and TG were measured.Result: The rat's serum TC and TG in Xi-zhi-jiang capsule treatment groups was lower than those of high lipid fed groups,and the difference was significant(P<0.05);the Xi-zhi-jiang capsule could remarkably lower the liver to the TC and TG of HL rat(P<0.01).Conclusion:The Xi-zhi-jiang capsule could lower serum and liver lipid of rats with hyperlipidemia. |
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| Keywords: | Hyperlipidemia Rats The Xi-zhi-jiang Capsule |
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