新鲜血小板与冰冻血小板输注效果比较

目的比较新鲜血小板与冰冻血小板的输注效果。方法将160例血小板减少或血小板功能障碍患者随机分为观察组（输注新鲜血小板，n=82）和对照组（输注冰冻血小板，n=78）。比较输注后两组患者的出血时间，输注后1h,24h外周血血小板增高校正指数（CCI）和血小板回收率（PPR）。结果观察组和对照组输注血小板后1h的出血时间无显著差异（P〉0．05）。观察组输注血小板后1h和24h的CCI值和PPR值高于对照组（P〈0．01）。结论新鲜血小板提高外周血血小板计数的作用优于冰冻血小板。

Comparison on the effectiveness of transfusion of fresh platelet and cryopreserved platelet

Objective To explore the effectiveness of fresh platelet-rich plasma transfusion and cryopreserved platelet transfusion.Methods One hundred and sixty patients with thrombocytopenia or platelet dysfunction were randomly divided into two groups.One group received transfusion of fresh platelet(experimental group)and the other was given cryopreserved platelet(control group).The hemostasis time,CCI and PPR of peripheral blood at 1 h and 24 h after platelet transfusion were compared between the two groups.Results There were significant differences in CCI and PPR between two groups at 1 h and 24 h after platelet transfusion(P<0.01).Conclusion Fresh platelet transfusion has better effect on raising platelet count in peripheral blood in comparison to cryopreserved platelet.