| 乙型肝炎病毒宫内感染及其相关因素的研究 |
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| 引用本文： | 门可,徐剑秋.乙型肝炎病毒宫内感染及其相关因素的研究[J].第四军医大学学报,1996,17(1):28-29. |
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| 作者姓名： | 门可 徐剑秋 |
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| 作者单位： | 第四军医大学流行病学教研室，陕西省妇幼保健院 |
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| 摘 要： | 追踪随访８１例乙型肝炎表面抗原（ＨＢｓＡｇ）阳性母亲所生婴儿，乙肝病毒宫内感染率为１３．６％，对国产血源性疫苗阳性反应率为８６．４％，通过分析母血ＨＢＶ标志，发现；（１）母血中ＨＢｓＡｇ高滴度，ｅ抗原阳性是宫内感染的重要危险因素；（２）宫内感染与婴儿免疫无应答有关。
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| 关 键 词： | 乙型肝炎病毒 宫内感染 免疫疗法 疫苗 |
A study of hepatitis B virus intrauterine infection and risk factor |
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| Men Ke ,Wang Fusheng ,Xu Dezhong ,Yan Yongping ,Xiao Leyi ,Zhang Jingxia ,Xu Jianqiu ,Yang Min ,Chen Xianghong.A study of hepatitis B virus intrauterine infection and risk factor[J].Journal of the Fourth Military Medical University,1996,17(1):28-29. |
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| Authors: | Men Ke Wang Fusheng Xu Dezhong Yan Yongping Xiao Leyi Zhang Jingxia Xu Jianqiu Yang Min Chen Xianghong |
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| Affiliation: | Men Ke 1,Wang Fusheng 1,Xu Dezhong 1,Yan Yongping 1,Xiao Leyi 1,Zhang Jingxia 1,Xu Jianqiu 2,Yang Min 2,Chen Xianghong 2 1Department of Epidemiology,Fourth Military Medical University,Xi'an 710033 2Maternal & Children Hospital o |
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| Abstract: | Eighty one infants borne by mothers who were HBsAg (+) carriers have been followed up. HBsAg, anti HBs, HBeAg were detected by ELISA. Results: HBV intrauterine infection rate is 13.6%, and effectiveness rate of HBV vaccine is 86.4%. Conclusions: (1) HBsAg high titers and HBeAg positive in mothers' blood samples are most important risk factors; (2) Nonresponders among infants have associated with intrauterine infection. |
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| Keywords: | hepatitis B virus intrauterine infection nonresponde to vaccine |
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