| 苯对雄性小鼠生殖细胞损伤的研究 |
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| 引用本文： | 朱玉芬,冯文君,李书香,吴勇全.苯对雄性小鼠生殖细胞损伤的研究[J].广东药学院学报,1988(2). |
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| 作者姓名： | 朱玉芬 冯文君 李书香 吴勇全 |
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| 作者单位： | 广东医药学院劳动卫生学教研室，广东医药学院劳动卫生学教研室，广东医药学院劳动卫生学教研室，广东医药学院劳动卫生学教研室 |
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| 摘 要： | 本研究以浓度为30mg/m~8,300mg/m~8、3000mg/m~8和30000mg/m~8的苯给小鼠静式吸入染毒,作精子畸形、初级精母细胞染色体畸变、精原细胞SCE三项检查。三个试验的结果一致,表明苯有性腺毒性作用,可诱发雄性小鼠生殖细胞突变
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| 关 键 词： | 苯 雄性小鼠 生殖细胞 染色体畸变 姐妹染色单体互换 精子畸形 |
STUDIES OF BENZENE ON GERM CELL DAMAGE OF MALE MICE |
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| Zhu YuFen.STUDIES OF BENZENE ON GERM CELL DAMAGE OF MALE MICE[J].Academic Journal of Guangdong College of Pharmacy,1988(2). |
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| Authors: | Zhu YuFen |
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| Affiliation: | Zhu YuFen Department of Industrial Hyigene Guangdong Medical and Pharmaceuticas College |
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| Abstract: | This study deals with the damage of benzene on germ cell of male mice. Male mice were exposed to 300mg/m~3, 300mg/m~3 3000mg/m~3 and 30000 mg/m~3 benzene vapor. Sperm abnormality, primary spermatoeyte chromoso- mal aberration and spermatogonia SCE were examined. The results were identity. This study showed that benzene has toxic effect on sex gland and induced mutation on germ cell of male mice. |
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| Keywords: | Benzene Male mice Germ cell primary spermatocyte chromosomal aberration Spermatogonia SCE Sperm abnormality |
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