| Effects of Minimally Invasive Puncture and Drainage of Intracranial Hematoma on the Blood-brain Barrier in Patients with Cerebral Hemorrhage |
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| 作者姓名： | 黄晓江 郭守刚 王伟 |
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| 作者单位： | Department of Neurology Tongji Hospital Tongji Medical College Huazhong University of Science and Technology，Department of Neurology Tongji Hospital Tongji Medical College Huazhong University of Science and Technology，Department of Neurology Tongji Hospital Tongji Medical College Huazhong University of Science and Technology，Wuhan 430030 China，Wuhan 430030 China，Wuhan 430030 China |
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| 摘 要： | The effects of minimally invasive surgery on the blood-brain barrier (BBB) of 30 patients with cerebral hemorrhage were investigated. Difference of the BBB index and serum MBP concentra-tion were assessed in 15 cases of conservative treatment group and 15 cases of minimally invasive surgery group. The BBB index in minimally invasive surgery group was significantly lower than in conservative treatment group (P<0.05), and the BBB index in the two treatment groups was signifi-cantly higher than in control group (P<0.01). Serum MBP concentration in minimally invasive sur-gery group was significantly lower than in conservative treatment group (P<0.05), and that in the two treatment groups was significantly higher than in control group (P<0.01). It was suggested the per-meability of BBB in patients with cerebral hemorrhage was increased, and BBB index and serum MBP concentration in patients with cerebral hemorrhage were increased. Minimally invasive surgery can reduce the lesion of cytotoxicity to BBB and cerebral edema.
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| 关 键 词： | 肿瘤入侵 头颅血肿 血脑屏障 治疗 |
| 收稿时间： | 2006-06-20 |
Effects of minimally invasive puncture and drainage of intracranial hematoma on the blood-brain barrier in patients with cerebral hemorrhage |
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| Huang?Xiaojiang,Guo?Shougang,Wang?Wei.Effects of Minimally Invasive Puncture and Drainage of Intracranial Hematoma on the Blood-brain Barrier in Patients with Cerebral Hemorrhage[J].Journal of Zuazhong University of Science and Technology: Medical Edition,2007,27(1):101-103. |
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| Authors: | Huang Xiaojiang Guo Shougang Wang Wei |
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| Affiliation: | Department of Neurology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China |
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| Abstract: | The effects of minimally invasive surgery on the blood-brain barrier (BBB) of 30 patients with cerebral hemorrhage were investigated. Difference of the BBB index and serum MBP concentra-tion were assessed in 15 cases of conservative treatment group and 15 cases of minimally invasive surgery group. The BBB index in minimally invasive surgery group was significantly lower than in conservative treatment group (P<0.05), and the BBB index in the two treatment groups was signifi-cantly higher than in control group (P<0.01). Serum MBP concentration in minimally invasive sur-gery group was significantly lower than in conservative treatment group (P<0.05), and that in the two treatment groups was significantly higher than in control group (P<0.01). It was suggested the per-meability of BBB in patients with cerebral hemorrhage was increased, and BBB index and serum MBP concentration in patients with cerebral hemorrhage were increased. Minimally invasive surgery can reduce the lesion of cytotoxicity to BBB and cerebral edema. |
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| Keywords: | intracerebral hemorrhage blood-brain barrier BBB index MBP |
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