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心脏起搏治疗对Ⅲ度房室传导阻滞患者血浆脑钠肽的影响
引用本文:雷甿甿,谢毅,吴立荣,马启玲,张长海.心脏起搏治疗对Ⅲ度房室传导阻滞患者血浆脑钠肽的影响[J].重庆医学,2008,37(23):2692-2693.
作者姓名:雷甿甿  谢毅  吴立荣  马启玲  张长海
作者单位:贵阳医学院附属医院心内科 550004;贵州省人民医院心内科,550002
摘    要:目的 探讨心脏起搏治疗对Ⅲ度房室传导阻滞(Ⅲ度AVB)患者血浆脑钠肽(BNP)的影响.方法 分别对20例Ⅲ度AVB患者及20例健康体检者(对照组)抽取静脉血备用,另对15例行临时心脏起搏治疗者分别于心脏起搏治疗前及起搏治疗24h后抽静脉血备用;用放射免疫法测定各组患者血浆BNP浓度进行统计分析.结果 Ⅲ度AVB患者血浆BNP浓度为(115±23)pg/mL,明显高于对照组的(27±14)pg/mL(P<0.01);15例行临时心脏起搏治疗者,起搏24h后血浆BNP浓度(40±13 Pg/mL)较起搏治疗前(103±17 pg/mL)明显降低(P<0.01),但仍未恢复至对照组水平.结论 心脏起搏治疗可使Ⅲ度AVB患者 已升高的血浆BNP浓度明显降低,并与患者血流动力学的恢复改善相一致.

关 键 词:Ⅲ度房室传导阻滞  脑钠肽  心脏起搏

Influence of pacing on plasma concentrations of brain natriuretic peptide in patients with third-degree atrioventricular block
LEI Mang-mang,XIE Yi,WU Li-rong,et al..Influence of pacing on plasma concentrations of brain natriuretic peptide in patients with third-degree atrioventricular block[J].Chongqing Medical Journal,2008,37(23):2692-2693.
Authors:LEI Mang-mang  XIE Yi  WU Li-rong  
Affiliation:LEI Mang-mang,XIE Yi,WU Li-rong,et al.(Department of Cardiology,Affiliated Hospital of Guiyang Medical College,Guiyang 550004,China)
Abstract:Objective To investigate the influence of pacing on plasma concentrations of brain natriuretic peptide(BNP) in the patients with third-degree atrioventricular block.Methods To measure the plasma concentrations of BNP in the patients with third-degree atrioventricular block and in control group,in the mean time,to compare the changes of concentrations before and after pacing in the patients with third-degree atrioventricular block.The plasma concentrations of BNP were determined with radioimmunoassay.Results...
Keywords:third-degree atrioventricular block  brain natriuretic peptide  cardiac pacing  
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