| 拉西地平合用阿托伐他汀对原发性高血压左室肥厚及舒张功能的影响 |
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| 引用本文： | 苟怀宇,陈艳秋.拉西地平合用阿托伐他汀对原发性高血压左室肥厚及舒张功能的影响[J].重庆医学,2009,38(12). |
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| 作者姓名： | 苟怀宇 陈艳秋 |
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| 作者单位： | 重庆市渝北区人民医院心内科,401120 |
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| 摘 要： | 目的 评价拉西地平合用阿托伐他汀对原发性原发性高血压左室肥厚及舒张功能的影响.方法 将90例原发性原发性高血压左室肥厚患者随机分为A、B两组,A组给予拉西地平4mg/d;B组给予拉西地平4mg/d+阿托伐他汀10 mg/d.疗程6个月.分别在用药前、用药后6个月应用超声心动图检查评价心肌肥厚和左室舒张功能.结果 两组治疗6个月后左室肥厚的逆转及舒张功能指标(E、A、E/A、IVRT)改善程度与用药前比较差异有统计学意义(P<0.05).两组间比较B组明显优于A组(P<0.01).结论 拉西地平合用阿托伐他汀对原发性高血压左室肥厚逆转及舒张功能改善有协同作用,较单一用药疗效显著.
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| 关 键 词： | 拉西地平 阿托伐他汀 原发性原发性高血压 左室肥厚 舒张功能 |
Effect of lacidipine combination of atorvastatin on left ventricular hypertrophy and diastolic function in hypertensive patients |
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| GOU Huai-yu,CHEN Yan-qiu.Effect of lacidipine combination of atorvastatin on left ventricular hypertrophy and diastolic function in hypertensive patients[J].Chongqing Medical Journal,2009,38(12). |
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| Authors: | GOU Huai-yu CHEN Yan-qiu |
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| Abstract: | Objective To evaluate effect of Lacidipine combination of atorvastatin on hypertensive left ventricular hypertrophy and diastolic function.Methods Ninety cases of hypertension in patients with left ventricular hypertrophy were randomly divided into A,B groups,Group A with lacidipine 4mg/d and Group B with Lacidipine 4mg/d and atorvastatin 10mg/d were treated for 6 months.left ventricular hypertrophy and diastolic function were evaluated by echocardiography before and after 6 months of treatment.Results Afte... |
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| Keywords: | lacidipine atorvastatin essential hypertension left ventricular hypertrophy diastolic function |
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