应用动态血糖监测系统评价2型糖尿病患者使用诺和锐30与诺和灵30R血糖漂移和低血糖发生率对比研究

目的:用动态血糖监测方法评价预混胰岛素类似物和预混胰岛素治疗2型糖尿病(T2DM)时血糖漂移和低血糖发生率的差异.方法:分别使用门冬胰岛素30注射液和预混人胰岛素30R注射液治疗2组T2DM患者,采用动态血糖监测系统检测的方法,评价2组患者血糖漂移和低血糖发生率的差异.结果:2种胰岛素都能有效控制血糖,门冬胰岛素30注射液组血糖漂移度小于预混人胰岛素30R注射液组,差异有统计学意义(P＜0.05),门冬胰岛素30组低血糖事件少于预混人胰岛素30R注射液,差异统计学意义(P＜0.05).结论:门冬胰岛素30注射液和预混人胰岛素30R注射液治疗T2DM,在血糖控制良好时,前者血糖漂移及低血糖发生率低于后者.

Evaluation of Premixed Insulin with Dynamic Glucose Monitoring Methods

Objective:Dynamic glucose monitoring methods for the evaluation of premixed insulin analogues and premixed insulin treatment of type 2 diabetes mellitus(T2DM) when blood glucose excursion and hypoglycemia incidence rate difference.Methods:Using insulin aspart 30 injection and premixed human insulin 30R injection on the treatment of 2 group T2DM patients,using dynamic blood glucose monitoring system detection method,evaluation of 2 groups of patients with blood glucose excursion and hypoglycemia incidence rate difference.Results:2 kinds of insulin can effectively control blood sugar,insulin aspart 30 injection blood glucose excursion lower than premixed human insulin 30 R injection group,the difference was statistically significant(P < 0.05),insulin aspart 30 groups of hypoglycemic events less than premixed human insulin 30 R injection,these differences were statistically significant(P < 0.05).Conclusion:Insulin aspart 30 injection and premixed human insulin 30 R injection in the treatment of T2DM,in well control of blood glucose,the glucose excursion and hypoglycemia incidence is lower than the latter.