| 杜仲内生真菌的分离鉴定及其对异甜菊醇的生物转化研究 |
| |
| 引用本文： | 陈峻青,王伊文,冯成亮,蔡进,吉民.杜仲内生真菌的分离鉴定及其对异甜菊醇的生物转化研究[J].东南大学学报(医学版),2011,30(6). |
| |
| 作者姓名： | 陈峻青 王伊文 冯成亮 蔡进 吉民 |
| |
| 作者单位： | 1. 东南大学化学化工学院,制药工程系,江苏,南京,211189
2. 解放军302医院,药学部,北京,100039 |
| |
| 基金项目： | 中华人民共和国卫生部资助项目(WKJ2005-2-022); 国家重点基础研究发展计划资助项目(2011CB933503) |
| |
| 摘 要： | 目的:从植物杜仲的根、茎、叶中分离内生真菌并进行初步鉴定,并研究获得的杜仲内生真菌对异甜菊醇的生物转化活性。方法:采用形态学方法对分离菌株进行鉴定,并对其进行异甜菊醇生物转化活性筛选实验。结果:从健康杜仲的根、茎、叶中分离获得52株内生真菌,属于2纲,2目,4科,10属。其中有4株内生真菌对异甜菊醇具有生物转化活性,分别为交链孢霉Alternaria sp.EL3、瘤座霉Tubercularia sp.ER3、镰孢霉Fusarium sp.EL7及青霉Penicillium sp.ES2。结论:杜仲内生真菌多样性丰富,部分内生真菌对异甜菊醇具有生物转化活性,具有很好的研究和应用价值。
|
| 关 键 词： | 杜仲 内生真菌 异甜菊醇 生物转化 |
Isolation and identification of endophytic fungi from Eucommia ulmoides and their biotransformation activity of isosteviol |
| |
| CHEN Jun-qing,WANG Yi-wen,FENG Cheng-liang,CAI Jin,JI Min.Isolation and identification of endophytic fungi from Eucommia ulmoides and their biotransformation activity of isosteviol[J].Journal of Southeast Univ: Medical Sci Ed,2011,30(6). |
| |
| Authors: | CHEN Jun-qing WANG Yi-wen FENG Cheng-liang CAI Jin JI Min |
| |
| Affiliation: | CHEN Jun-qing1,WANG Yi-wen2,FENG Cheng-liang1,CAI Jin1,JI Min1(1.Department of Pharmaceutical Engineering,School of Chemistry and Chemical Engineering,Southeast University,Nanjing 211189,China,2.Pharmacy Department,302 Hospital of PLA,Beijing 100039,China) |
| |
| Abstract: | Objective: To isolate and identify some endophytic fungi from the root,stem and leaf of Eucommia ulmoides and to test their biotransformation activity of isosteviol.Methods: Endophytic fungi were morphologically identified and their biotransformation activity of isosteviol were screened.Results: 52 strains of endophytic fungi were isolated from Eucommia ulmoides,among which 4 strains presented biotransformation activity of isosteviol.Conclusion: The endophytic fungi of Eucommia ulmoides is diversiform and r... |
| |
| Keywords: | Eucommia ulmoides endophytic fungi isosteviol biotransformation |
| 本文献已被 CNKI 万方数据 等数据库收录！ |
|
