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CA125、CA72-4的检测在卵巢癌早期诊断中的临床价值
引用本文:郭少磊,高美华,李武伦.CA125、CA72-4的检测在卵巢癌早期诊断中的临床价值[J].中国医疗前沿,2008,3(6).
作者姓名:郭少磊  高美华  李武伦
作者单位:郭少磊,李武伦,Guo Shaolei,Yu Tongbo(青岛大学医学院附属青岛市第八人民医院检验科,山东,青岛,266100);高美华,Li Wulun(青岛大学医学院,山东,青岛,266100)
摘    要:目的讨论联合检测血清CA125和CA72-4的含量对卵巢癌早期诊断的临床价值。方法用电化学发光免疫测定法测定卵巢癌患者94例,卵巢良性肿瘤患者136例,及健康妇女80例的血清样品中CA125和CA72-4含量。结果与卵巢良性肿瘤组和健康妇女组相比,卵巢癌患者血清CA125和CA72-4的含量和阳性率明显升高(P<0.01),两项标志物的阳性率分别是87.23%和68.08%,联合检测阳性率为91.5%。结论两项肿瘤标志物对卵巢肿瘤的良恶性辅助诊断及鉴别诊断具有一定应用价值,联合检测可以提高早期卵巢癌的阳性诊断率。

关 键 词:卵巢癌  CA125  CA72-4  电化学发光

Value of serum CA125 and CA72-4 detect ion in ovarian tumors
Guo Shaolei,Li Wulun,Yu Tongbo.Value of serum CA125 and CA72-4 detect ion in ovarian tumors[J].China Healthcare Innovation,2008,3(6).
Authors:Guo Shaolei  Li Wulun  Yu Tongbo
Affiliation:Guo Shaolei Li Wulun Yu Tongbo;
Abstract:obiective To study the clinical value of combined detect ion of the serum levels of CA 125,CA72-4 in the diagnosis of ovary cancer and the observat ion of the curat ive effect.Methods Serum levels of CA 125,CA72-4 in 94 patients with ovary cancer,136 patients with benign ovary tumor and 80 normal controls were measured by elctrochemilum-inescence immuno-assay(ECLIA).Results The levels of CA 125,CA72-4 in ovary cancer group were significantly higher than those in benign ovary tumo r and normal control groups...
Keywords:CA72-4
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