| 益气活血方对实验性高脂血症大鼠血脂及载脂蛋白的影响 |
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| 引用本文： | 安建峰,张金虎,汪静.益气活血方对实验性高脂血症大鼠血脂及载脂蛋白的影响[J].陕西中医学院学报,2010,33(5):81-83. |
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| 作者姓名： | 安建峰 张金虎 汪静 |
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| 作者单位： | 1. 西安市儿童医院中西医结合科,陕西,西安,710003
2. 西安市儿童医院PICU,陕西,西安,710003 |
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| 摘 要： | 日的观察益气活血对高脂血症动物模型血清中TC、TG、LDL—CxHDL—c、ApoAI、ApoB100的含量的影响，探讨益气活血法在治疗高脂血症中的作用及各项指标的变化与剂量之间的关系。方法选SD大鼠60只，随机分为六组，造高脂血症模型后，分别给予益气活血方高、中、低剂量及非诺贝特治疗，从腹主动脉取血，检测TC、TG、LDL—c、HDL—c、ApoAI、ApoB100的含量。结果益气活血方能显著降低大鼠血清中TG、TC、LDL—c、APOB100水平，显著提高大鼠血清中HDL—C和APOAI水平，并有一定的量效关系。
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| 关 键 词： | 益气活血方 高脂血症 实验研究 |
Effect of Yiqihuoxue Formula on blood fat and apoliprotein of experimental hyperlipemia rats |
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| An Jianfeng,Zhang Jinhu,Wang Jing.Effect of Yiqihuoxue Formula on blood fat and apoliprotein of experimental hyperlipemia rats[J].Journal of Shaanxi College of Traditional Chinese Medicine,2010,33(5):81-83. |
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| Authors: | An Jianfeng Zhang Jinhu Wang Jing |
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| Affiliation: | An Jianfeng Zhang Jinhu Wang Jing Integrated western and Chinese medicine depart. Of Xi＇an Children Hospital, Xi＇an, Shaanxi, 710003; 2. PICU of Xi＇an Children Hospital, Xi＇an, Shaanxi, 710003) |
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| Abstract: | Objective To observe Yiqihuoxue Formula＇s effect on content of TC, TG, LDL- c, HDL- c, ApoAI,ApoB100 of hyperlipemia rats. Methods the total of 60 SD rats were divided randomly into six groups. After models were made, rats were treated with high, middle, low dosage Yiqihuoxue Formula, fenofibrate, and then TC ,TG ,LDL - c ,HDL - c ,ApoAI ,ApoB100 were tested. Results Yiqihuoxue Formula lowered level of TC, TG,LDL - c ,and ApoB100 significantly, while raised HDL - c and ApoAI level. Dose - effect relationship was presented. |
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| Keywords: | Yiqihuoxue Formula hyperlipemia experimentalize |
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