| 依达拉奉对急性脑梗死血清神经元特异性烯醇化酶的影响 |
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| 引用本文： | 林航,徐格林,林敏.依达拉奉对急性脑梗死血清神经元特异性烯醇化酶的影响[J].医学研究生学报,2006,19(7):607-609. |
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| 作者姓名： | 林航 徐格林 林敏 |
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| 作者单位： | 1. 南京军区福州总医院神经内科,福建福州,350025
2. 南京军区南京总医院神经内科,江苏南京,210002 |
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| 摘 要： | 目的：观察依达拉奉注射液对急性脑梗死患者血液中神经元特异性烯醇化酶（NSE）的影响，探讨依达拉奉注射液的脑保护作用。方法：利用酶联免疫吸附法检测35例脑梗死患者依达拉奉注射液治疗过程中血清中NSE浓度，记录神经功能缺损评分、评定临床疗效。并与对照组进行比较。结果：依达拉奉注射液治疗第3d时，治疗组患者血液中NSE浓度即明显下降，低于对照组，神经功能缺损评分亦明显少于对照组（P〈0．01）。21d时依达拉奉组神经功能改善的总有效率为62．86％，常规治疗组为34．29％。结论：依达拉奉注射液对急性脑梗死的神经元有保护作用，能有效改善急性脑梗死患者的神经功能缺损。
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| 关 键 词： | 依达拉奉 神经元特异性烯醇化酶 脑梗死 |
| 文章编号： | 1008-8199(2006)07-0607-03 |
| 修稿时间： | 2005年12月23 |
Effect of the edaravone injection on the neuron-specific enolase in serum from patients with acute cerebral infarction |
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| LIN Hang,XU Ge-lin,LIN Ming.Effect of the edaravone injection on the neuron-specific enolase in serum from patients with acute cerebral infarction[J].Bulletin of Medical Postgraduate,2006,19(7):607-609. |
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| Authors: | LIN Hang XU Ge-lin LIN Ming |
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| Abstract: | Objective:To investigate the effect of edaravone injection on the neuron-specific enolase(NSE) concentration in serum from patients with acute cerebral infarction.Methods:The NSE concentrations in serum from 35 patients were measured by an ELISA method.Neurological deficit was scored for clinical effect assessment.Results:Serum NSE levels and neurological deficit scores in edaravone treating group significantly decreased at d 3 compared with those in routine therapy group((P<)0.01).The efficiency rate was 62.86 % in edaravone treating group,and 34.29 % in routine therapy group at d 21.Conclusion:Edaravone injection can protect brain tissue from acute cerebral infarction and lessen nerve function impairment. |
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| Keywords: | Edaravone Neuron-specific enolase Cerebral infarction |
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