冠心病中医证候疗效评价研究

目的:探讨以证候为内容的冠心病中医疗效评价方法,并验证可靠性。方法:以100 mm刻度法及综合评价层次分析法(AHP)为数学工具,以"综合集成研讨厅"为研讨方式,共取57个中医症状量化值为底层指标,以11个基本证候为第二层次指标,以实证与虚证为第三层次指标,以证候总评分为顶层指标,初步构建了以证候为内容的冠心病层次分析综合疗效评价方法。并在临床上与心绞痛评分、西雅图心绞痛评分、生存质量(SF-36)等进行了相关性对比研究,对模型的可靠性进行了验证。结果:冠心病证候总评分与心绞痛评分、西雅图心绞痛评分、SF-36有显著的相关性。结论:构建的以证候为内容的冠心病中医综合疗效评价方法可评价冠心病的轻重程度。

Construction of therapeutic evaluation system for patients with coronary heart disease in traditional Chinese medicine

Objective:To construct a system of therapeutic evaluation for patients with coronary heart disease(CHD) according to the theory of syndrome differentiation in traditional Chinese medicine(TCM),and to examine its reliability.Methods:Analytic hierarchy process(AHP)and 100 mm surveyors rod method were applied as a mathematical tool,"hall for workshop of metasynthetic engineering" was applied as an important way of discussion,total 57 symptoms of TCM were selected as the underlying index,11 basic syndromes of TCM and excessive syndromes and deficient syndromes were applied as a second-level indicators and third-level indicators,the total assessment of TCM syndromes was applied as a top-level indicator,initially constructed to the comprehensive clinical evaluation system for CHD,symptoms of TCM as its content.And its reliability was verified in clinical practice by comparing with some evaluation criteria in western medicine,such as angina pectoris score;Seattle angina score;and quality of life(SF-36),etc.Results:A system of therapeutic effect evaluation was constructed,and the comparative study with western medicine targets,the total score of TCM syndromes has a significant correlation with angina pectoris score,the Seattle angina score,quality of life(SF-36),and it could reflect the progress of CHD and quality of life in patients.Conclusion:The system of therapeutic effect evaluation on CHD can reflect the severity of disease and characteristics of TCM treatment.