维吾尔族和汉族早发冠心病危险因素及中医证型对比研究

目的探讨维吾尔族与汉族早发冠心病（CHD）患者危险因素及中医证型的差异。方法研究对象为2010年7月—2011年11月住院行冠状动脉造影确诊为早发CHD患者660例,按不同民族分为两组,汉族384例,维吾尔族276例。结果维吾尔族早发CHD组年龄、性别、血脂代谢紊乱、超重等方面与汉族早发（HD）组比较有统计学意义（P〈0.01）;低密度脂蛋白（LDL-C）、血浆纤维蛋白原（Fib）与汉族早发（HD）组比较有统计学意义（P〈0.01）;维吾尔族中最常见证型依次是秽浊痰阻、气虚血瘀、痰阻心脉、心血瘀阻、气滞血瘀、阴寒凝滞、气阴两虚、心肾阴虚、阳气虚衰。汉族中最常见证型依次是秽浊痰阻、气虚血瘀、心血瘀阻、气滞血瘀、痰阻心脉、气阴两虚、心肾阴虚、阴寒凝滞、阳气虚衰。秽浊痰阻、气虚血瘀是两组最主要中医证型（维吾尔族67.8%,汉族63.0%）,其次是心血瘀阻、气滞血瘀和痰阻心脉,但无明显统计学意义。结论新疆维吾尔族早发CHD患者超重、年龄、性别、血脂代谢紊乱、高LDL-C、Fib水平等与汉族早发组比较有统计学意义,且有多种危险因素。秽浊痰阻、气虚血瘀是两组最主要的中医证型,其次是心血瘀阻、气滞血瘀和痰阻心脉。

Comparison of Risk Factors and TCM Syndrome in Premature Coronary Heart Disease between Uygur Race and Han Race

Objective To compare and analyze the difference of risk factors and traditional Chinese medicine（TCM） syndrome in patients（pts） with premature coronary heart disease（CHD） between Uygur race and Han race in Xinjiang.Methods A total of 660 pts with premature CHD were diagnosed by coronary angiography（CAG） and divided into Uygur race group（n=276） and Han race group（n=384）.Data of pts with premature CHD were collected.Results There were difference in age,sex,hyperlipaemia,and overweight between Uygur race group and Han race group（P0.01）.More Uygur pts had higher low density lipoprotein（LDL-C） and fibrinogen（Fib） than that in Han（P0.01）.More Uygur pts were with turbid sputum,qi deficiency and blood stasis,phlegm in heart,blockage of heart blood stasis,qi stgnation and blood stasis,yin-deficiency of heart and kidney,phlegm blocking,stagnation of qi due to cold,dual deficiency yang and qi.More Han pts were with turbid sputum,qi deficiency and blood stasis,blockage of heart blood stasis,qi stagnation and blood stasis,phlegm in heart,deficiency of heart and kidney yin /phlegm blocking,dual deficiency yang and qi.Turbid sputum,qi deficiency and blood stasis were main TCM syndrome type in two race（Uygur pts 67.8%,Han pts 63%）.The second TCM syndrome type was blockage of heart blood stasis,qi stagnation and blood stasis,phlegm in heart vessel（P0.05）.Conclusion Premature CHD age,sex,hyperlipaemia,overweight,higher LDL-C and Fib in pts with premature CHD were different between Xinjiang Uyghur race and Han race.The turbid sputum,qi deficiency and blood stasis were the main TCM syndrome typein two groups.The second TCM syndrome types were blockage of heart blood stasis,qi stagnation and blood stasis,phlegm in heart vessel in Uygur pts.