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蒙药三子胶囊剂成型工艺研究
引用本文:王烈群,温爱平,新燕,余东海,刘晓虎.蒙药三子胶囊剂成型工艺研究[J].时珍国医国药,2006,17(4):537-539.
作者姓名:王烈群  温爱平  新燕  余东海  刘晓虎
作者单位:1. 内蒙古医学院药学院,内蒙古,呼和浩特,010059
2. 内蒙古医学院基础医学院微生物免疫教研室,内蒙古,呼和浩特,010059
基金项目:内蒙古自治区自然科学基金资助(No.20001306)
摘    要:目的研究蒙药三子胶囊剂的成型工艺及质量控制标准。方法通过测定内容物的休止角、堆密度、吸湿率等确定最佳成型工艺;采用高效液相色谱法(HPLC)测定三子胶囊剂中有效成分栀子苷含量。结果三子胶囊内容物含药材细粉30%时,25℃吸湿率为5.46%,临界相对湿度(CRH)为75%;胶囊中栀子苷含量控制约为12.61~15.30 mg/粒。结论以此工艺制备三子胶囊质量符合相关要求。

关 键 词:蒙药  三子胶囊剂  成型工艺
文章编号:1008-0805(2006)04-0537-02
收稿时间:2005-06-14
修稿时间:2006-02-23

Studies on the Process of Mongolian Medicine Sanzi Capsules
WANG Lie-qun,WEN Ai-ping,XIN Yan,YU Dong-hai,LIU Xiao-hu.Studies on the Process of Mongolian Medicine Sanzi Capsules[J].Lishizhen Medicine and Materia Medica Research,2006,17(4):537-539.
Authors:WANG Lie-qun  WEN Ai-ping  XIN Yan  YU Dong-hai  LIU Xiao-hu
Affiliation:1. Pharmaceutical Department of Inner Mongolian Medical College, Huhhot, 010059, China ; 2. Basical Medical School of Inner Mongolian Medical College, Huhhot 010059, China; 3. Graduate of 2002, Inner Mongolian Medical College, Huhhot 010059, China
Abstract:Objective:To investigate the optimum process and quality standard of Mongolian medicine Sanzi Capsules.Methods:The content of jasminoidin was determined with HPLC,and repose angle,stack density and hygroscopic rate of the content were measured.Results:The content of jasminoidin in Sanzi Capsules was 12.61~15.30 mg/capsule.Conclusion:The optimum process is established.
Keywords:Traditional Mongolian Medicine  Sanzi Capsules  Process  
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