| 腹泻清颗粒剂的质量标准研究 |
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| 引用本文： | 时维静,李立顺,陆凤琪,陈文成.腹泻清颗粒剂的质量标准研究[J].中医药学刊,2009(2):299-301. |
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| 作者姓名： | 时维静 李立顺 陆凤琪 陈文成 |
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| 作者单位： | 安徽科技学院,安徽凤阳233100 |
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| 基金项目： | 安徽省科技厅科技攻关重点项目资助（07010300153）;蚌埠市科技局产学研资助项目（2007） |
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| 摘 要： | 目的：建立腹泻清颗粒剂的质量控制方法。方法：采用TLC法对处方中的黄连、葛根、秦皮、地榆进行鉴别;采用HPLC法测定盐酸小檗碱的含量。结果：在薄层色谱中能检出黄连、葛根、秦皮、地榆;盐酸小檗碱在0.46~4.6μg范围内线性关系良好,r=0.9998,平均回收率为96.8%,RSD为0.41%。结论：该方法准确、可靠,能有效控制该制剂的质量。
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| 关 键 词： | 腹泻清颗粒剂 盐酸小檗碱 TLC HPLC |
Study on Quality Standard of Fuxieqing Granule |
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| SHI Wei-jing,LI Li-shun,LU Feng-qi,CHEN Wen-cheng.Study on Quality Standard of Fuxieqing Granule[J].Study Journal of Traditional Chinese Medicine,2009(2):299-301. |
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| Authors: | SHI Wei-jing LI Li-shun LU Feng-qi CHEN Wen-cheng |
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| Affiliation: | ( Anhui Science and Technology University, Fengyang 233100, Anhui, China) |
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| Abstract: | Objective ： To establish the quality standard of Fuxieqing granulas. Methods ： Radix Pulsatillae Chinensis, Coptis chinensis Franch, Fraxinus paxiana Lingelsh and Radix Glycyrrhizae were identified by TLC, and the content of Berberine Hydrochloride was determined by HPLC. Results：Radix Pulsatillae Chinensis, Coptis chinensis Franch, Fraxinus paxiana Lingelsh and Radix Glycyrrhizae could be detected by TLC. Berberine Hydrochloride showed a good linear relationship within the range of 0.46 - 4. 6μg, r = 0. 9998. The average recovery was 96. 8%, and RSD was 0.41%. Conclusion ：The method was accurate, reliable and could control the quality of this preparation. |
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| Keywords: | fuxieqing granula berberine hydrochloride TLC HPLC |
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