丁书文教授用药规律的计算机辅助分析——治疗心动过速用药分析

目的]探讨丁书文教授治疗心动过速的用药规律。方法]应用中医门诊电子病历收集丁书文教授心动过速医案74份,其他疾病医案1026份,并通过SAS统计软件编制了用药频率表,以心动过速为因变量、以用药频率≥10%的37种中药为自变量进行了Logistic回归分析。结果]在74份医案中,共用中药99种;其中次数最多者为黄芪,共63次,频率为85.14%;次数最少者为柴胡等27种,仅用1次,频率为1.35%;黄芪、当归、黄连、麦门冬、炒酸枣仁、五味子、紫石英、连翘、川芎、木香、砂仁、玫瑰花和人参偏回归系数的假设检验具有统计学意义(P<0.05)。结论]丁书文教授治疗心动过速,喜用黄芪、当归、黄连、麦门冬、炒酸枣仁、五味子、紫石英、连翘、川芎、木香、砂仁、玫瑰花和人参。

Auxiliary Analysis with Computer on Drug administration of Professor Ding Shu-wen in Treating Tachycardia

Objective] To explore the medication rule of Professor Ding Shu-wen in treating tachycardia. Methods] Seventy-four medical records were collected and the medication frequency table was set up with SAS statistical software. Logistic regression analysis was performed taking tachycardia as the dependent variable and 37 categories of Chinese medicines with medication frenquency more than or equal to 10% as the independent variable. Results] There were 99 species of traditional Chinese medicine used in the 74 medical cases. The astragali was the most utilized one. It was used 63 times altogether and the medication frenquency 85.14%. The least used were 27 categories of Chinese medicine, including bupleuri, etc. They were used only one time and the medication frequency was 1.35%. The hypothesis test of skew regression coefficient showed statistical significance in some medicines. They were astragali, angelica, coptidis rhizome, ophiopogonis tuber, stir-baked semen ziziphi spinosae, fructus schizandrae, amethyst, forsythia suspense, chuanxiong, ligustici, aucklandiae, villous amomum fruit, rosae rugosae, ginseng(P<0.05). Conclusions] Professor Ding Shu-wen loves to use astragali, angelica, coptidis rhizome, ophiopogonis tuber, stir-baked semen ziziphi spinosae, fructus schizandrae, amethyst, forsythia suspense, chuanxiong, ligustici, aucklandiae, villous amomum fruit, rosae rugosae, ginseng on treating tachycardia.