| 恶露不尽血瘀证型动物模型建立及评价标准和作用机制研究 |
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| 引用本文： | 王晓东,李莉,张婷婷,邓居桥,蒋浩.恶露不尽血瘀证型动物模型建立及评价标准和作用机制研究[J].中国中医基础医学杂志,2011(11). |
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| 作者姓名： | 王晓东 李莉 张婷婷 邓居桥 蒋浩 |
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| 作者单位： | 四川省中医药科学院; |
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| 基金项目： | 四川省中医药管理局2008年度中医药基础科研基金项目(2008-21) |
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| 摘 要： | 目的:建立寒湿合并抗早孕药物引起的大鼠恶露不尽血瘀证型动物模型。方法:冰水冷浸及米非司酮配伍米索前列醇灌胃早孕大鼠。结果:可致早孕大鼠出现血瘀样恶露量减少和舌色绛紫舌苔厚舌质湿腻等症状。结论:本模型可作为血瘀证型恶露不尽防治研究的药效评价实用模型。
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| 关 键 词： | 恶露不尽 大鼠 血瘀证 实验研究 |
Establishment,evaluation criterion and mechanism of post-natal lochia endless rats model with syndrome of blood stasis |
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| WANG Xiao-dong,LI Li,ZHANG Ting-ting,DENG Ju-qiao,JIANG Hao.Establishment,evaluation criterion and mechanism of post-natal lochia endless rats model with syndrome of blood stasis[J].Chinese Journal of Basic Medicine In Traditional Chinese Medicine,2011(11). |
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| Authors: | WANG Xiao-dong LI Li ZHANG Ting-ting DENG Ju-qiao JIANG Hao |
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| Affiliation: | WANG Xiao-dong,LI Li,ZHANG Ting-ting,DENG Ju-qiao,JIANG Hao(Sichuan Academy of Chinese Medicine Sciences,Chengdu 610041) |
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| Abstract: | Objective: To establish animal model for blood-stasis postpartum lochiorrhea induced by contraceptive drugs for early-pregnancy in cold-wet rats.Methods: Mifepristone and Misoprostol were given to early pregnant rats(immersed in frozen water in advance) orally.Results: The amount of blood stasis in the rats was decreased.There also appeared some symptoms,including purple tongue color,thick tongue fur,and moist tongue quality.Conclusion: This model can be used in the pharmacological studies of new drugs for ... |
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| Keywords: | postpartum lochiorrhea rat blood-stasis syndrome experimental study |
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