补肾调冲法诱发排卵的临床研究

目的：观察补肾调冲法对治疗功能性无排卵患者的保排卵作用。方法：将60例无排卵患者随机分成2组各30例。治疗组根据补肾调冲法则，以自拟补肾益冲汤（熟地黄、当归、白芍、山茱萸、黄精、紫河车粉、鹿角胶、续断、菟丝子、巴戟天、淫羊霍、香附）和活血调冲汤（当归、川芎、红花、桃仁、皂角刺、泽兰、赤芍、牡丹皮、穿山甲、党参、菟丝子、枸杞子、黄芪）按月经不同阶段治疗；对照组以克罗米芬、己烯雌酚、安宫黄体酮治疗。疗程均为6个月经周期。B超观察排卵情况、血雌二醇（E2）、孕酮（P）及主卵泡增长等指标。结果：2组患者E2和P水平显著提高，主卵泡直径明显增大，治疗前后比较，差异有显著性意义（P＜0．01）；2组治疗后比较，差异无显著性意义（P＞0．05）。治疗组180个周期，出现排卵90个周期，痊愈率达76．7％；对照组180个周期，出现排卵92个周期，痊愈率达83．3％。2组总和效率比较，差异无显著性意义（P＜0．05）。结论：补肾调冲法具有较好的促进E2和P正常分泌、使主卵泡直径增大和诱发排卵的作用。

A Clinical Study on Inducement of Ovulation by Kidney - Invigorating And Chong - Vessel - Regulating

Objective:To observe the ovulation-promoting action of kidney-invigorating and Chong-Vessel-regulating (KICR) therapy for functional anovulation (FA).Methods:60 cases of FA were allocated to two groups randomly.The treatment group (30 cases) treated by Bushen Yichong Tang (including Radix Rehmanniae preaparata,Radix Angelicae Sinensis,Radix Paeoniae Alba,Fructus Corni,Rhizoma Polygonati,Pulvis Placentae Hominis,Colla Corus Cervi,Radix Dipsaci,Semen Cuscutae,Radix Morindae Officinalis,Herba Epimedii and Rhizoma Cyperi) and Huoxue Tiaochong Tang (including Radix Angelicae Sinensis,Rhizoma Chuanxiong,Flos Carthami,Semen Persicae,Spina Gleditsae,Herba Lycopi,Radix Peeoniae Rubra,Cortex Moutan,Squama Mannis,Radix Codonopsis,Semen Cuscutae,Fructus Lycii and Radix Astragali) in accordance with different stages of menstruation.The control group (30 cases) treated by colmiphene,stilbestrol and provera.Six menstrual cycles constituted a course of treatment.The ovulation was detected by ultrasonography,and blood estradiol (E2),progestin (P) and the increase of main follicle were observed.Results:The level of E2 and P were markedly increased and the diameter of main follicle was markedly enlarged in two groups showing markedly significant difference after treatment (P < 0.01),but no significant difference between two groups (P > 0.05).Among 180 cycles,ovulation appeared 90 cycles in treatment group,the cured rate being 76.7%and 92 cycles and 83.3%respectively in control group (P > 0.05) . Conclusion:The KICR therapy possesses a good effect to promote the normal secretion of E2 and P,enlarge the diameter of main follicle and induce ovulation.