基于Citespace的中医药治疗过敏性紫癜可视化分析

目的:挖掘中医药治疗过敏性紫癜(HSP)的主要研究内容、研究前沿、作者合作网络、机构合作网络,为中医药治疗HSP的研究和发展提供参考。方法:利用Citespace("引文空间")软件系统对从中国知网数据库检索到的2878篇中医药治疗HSP相关文献进行可视化分析,对文献关键词进行聚类分析、突现分析,对作者、机构内容进行共现分析。结果:自1995年开始相关文献数量增长速度逐渐加快,2005年以后每年发表文献数量均稳定在100篇以上;聚类分析得到32个聚类,由396个节点,638条线组成,主要聚类结果包括小儿过敏性紫癜、活血化瘀药、紫癜性肾炎、凉血药、临床观察等;突现分析得出52个突现词,可看出中医药治疗HSP在治法上以凉血为主,其次是活血祛瘀和清热,常用药为牡丹皮、生地黄、赤芍等,病证表现上肾脏损伤的相关研究较多,临床上较重视名医经验、小儿过敏性紫癜的研究等;作者合作网络得到以丁樱、孙轶秋、何平为核心的3个主要合作团队图谱;机构合作网络分布图谱密度Density=0.0071。结论:中医药治疗HSP主要研究内容包括小儿过敏性紫癜、活血化瘀药、紫癜性肾炎、凉血药、临床观察等,当前的研究热点以小儿过敏性紫癜、名医经验、紫癜性肾炎、临床疗效为主,已形成相对较稳定的若干研究团队,但在机构合作上联系较为分散。

Visualization Analysis of Henoch-schonlein Purpura Treated by Traditional Chinese Medicine Based on Citespace

Objective: To finding the main research contents,research frontier,author and institutional cooperation of traditional Chinese medicine(TCM) for treating henoch-schonlein purpura(HSP).Providing reference for the research and development of TCM for treating the disease. Method: Using Citespace to analyze 2 878 TCM articles related to HSP retrieved from CNKI,cluster analysis and burst analysis of literature keywords,co-occurring authors and institutional cooperation analysis. Result: Since 1995,the number of related literature was growing rapidly and had been stable at more than 100 per year after 2005.Cluster analysis showed 32 clusters,consisting of 396 nodes and 638 lines. The main clustering results include Children with allergic purpura,blood-activating and stasis-resolving drug,Henoch-Schonlein purpura nephritis,blood-cooling drugs,clinical observation,etc. Break analysis yielded 52 emergent words. It can be seen that TCM treatment of HSP is mainly based on cooling blood,followed by activating blood to eliminate stagnation and clearing heat. Commonly used drugs are Moutan Cortex,Paeoniae Radix Rubra,and Rehmanniae Radix,etc. Clinically,it pays more attention to the experience of famous doctors,research on Children with allergic purpura,etc.The author''s cooperation network has obtained the maps of the three main cooperation teams with DING Ying,SUN Yi-qiu and HE Ping as the core. The Density of institutional cooperation network is 0.007 1. Conclusion: The main research contents of TCM for treating HSP include Children with allergic purpura,blood-activating and stasis-resolving drug,HSP nephritis,blood-cooling drugs,clinical observation,etc. Children with allergic purpura,experience from famous doctor,HSP nephritis and clinical efficacy is the foremost current research hotspot. A number of research teams have been formed that are relatively stable,but the institutional cooperation is scattered.