非小细胞肺癌不同病理分类与中医证候分布规律关系探讨

目的探讨中晚期非小细胞肺癌(NSCLC)患者病理分类与中医证候的关系。方法采用前瞻性临床研究方法,根据预先设计的观察表和临床证候诊断标准,按八纲、气血及脏腑辨证的原则,对中晚期NSCLC患者进行详细的中医辨证分型,并进行统计学处理分析。结果NSCLC在腺癌、鳞癌中出现较多的证型有:气虚,分别为114例次(36.08%)、69例次(28.63%);血瘀,分别为80例次(25.32%)、54例次(22.41%);痰湿,分别为43例次(13.61%)、35例次(14.52%);阴虚,分别为30例次(9.49%)、31例次(12.86%)。这些证型出现的频度在鳞癌和腺癌之间无明显差异(P>0.05)。结论腺癌、鳞癌证候均以气虚、血瘀证候为主,气虚中尤以肺、脾气虚证最多。这些证型出现的频度在鳞癌和腺癌之间无明显差异。

The Relationship between Pathological Types and Syndromes of TCM in Non-small Cell Lung Cancer

Objective To explore the relationship between pathological types and syndromes of TCM in non-small cell lung cancer (NSCLC). Methods Based on the theory of Ba-Gang, Zang-Fu organs and Qi-Blood, making and filling in the observation form of syndromes of TCM in patients with NSCLC and analysed by SPSS 11.5 statistics software. Results Deficiency of Qi, Blood stasis, damp-phlegm and deficiency of Yin are main syndromes of TCM in adenocarcinoma and squamous carcinoma of NSCLC (114, 69 times;80, 54 times;43, 35 times;30, 31 times respectively). There are not significant difference between adenocarcinoma and squamous carcinoma on syndromes of TCM (P >0.05). Conclusion Deficiency of Qi, Blood stasis, Damp-phlegm and Deficiency of Yin are main syndromes of TCM in adenocarcinoma and squamous carcinoma. In Deficiency of Qi, lung-deficiency of Qi and spleen-deficiency of Qi are common syndromes of TCM. Appearing frequency of syndromes of TCM between adenocarcinoma and squamous carcinoma is similar.