| 急性脑梗死中医证型与红细胞及血小板参数的相关性分析 |
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| 引用本文： | 吴学兵,;余志良,;王新华,;李博,;沈海涛,;韩海燕,;符布清.急性脑梗死中医证型与红细胞及血小板参数的相关性分析[J].辽宁中医杂志,2014(8):1673-1675. |
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| 作者姓名： | 吴学兵 ;余志良 ;王新华 ;李博 ;沈海涛 ;韩海燕 ;符布清 |
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| 作者单位： | [1]上海第七人民医院医学检验科,上海200137; [2]上海第七人民医院脑病科,上海200137; [3]上海第七人民医院肾病科,上海200137; [4]江苏省中医院检验科,江苏南京210029 |
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| 摘 要： | 目的:探讨红细胞和血小板参数与急性脑梗死不同中医证型的相关性。方法:对187例急性脑梗死不同中医证型患者和50例健康对照组的红细胞体积分布宽度(RDW)及血小板参数的血小板平均体积(MPV)、血小板压积(PCT)、血小板体积分布宽度(PDW)测定。结果:187例急性脑梗死患者中气虚血瘀型111例(59.4%),风痰阻络型68例(36.4%),肝阳暴亢,风火上扰证型8例(4.2%),证型分布以气虚血瘀型多见。气虚血瘀和肝阳暴亢,风火上扰证型的红细胞分布宽度(REW)与正常对照组有统计学上明显差异(P<0.05),同时气虚血瘀和肝阳暴亢,风火上扰证型的REW之间有统计学上明显差异(P<0.05);在血小板参数中,气虚血瘀和痰湿阻络型的血小板的平均体积(MPV)与正常对照组在统计学上有明显差异(P<0.05)。结论:急性脑梗死患者RDW和MPV临床上应用很广泛、简单易行、费用少、可在基层医院推广,为进一步探索中西医结合诊治脑梗死可提供病理生理基础。
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| 关 键 词： | 急性脑梗死 中医证型 红细胞及血小板参数 |
Analysis of Relationship between TCM Syndromes of Acute Cerebral Infarction and Red Blood Cell and Platelet Parameters |
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| Affiliation: | WU Xuebing , YU Zhiliang , WANG Xinhua , LI Bu , SHEN Haitao , HANG Haiyan , Fu Buqing ( 1. Department of Laboratory, Shanghai Seventh People＇ s Hospital, Shanghai 200157, China; 2. Department of Neurology, Shanghai Seventh People＇s Hospital, Shanghai 200137, China; 3. Department of Renal Medicine, Shanghai Seventh People＇s Hospital, Shanghai 200137, China; 4. Department of Laboratory Medicine of Jiangsu Province Hospital of TCM, Nanjing 210029 ,Jiangsu, China) |
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| Abstract: | Objective：To investigate the correlation between different syndrome types of traditional Chinese medicine and redblood cell and platelet parameters of acute cerebral infarction. Methods：Red cell volume distribution width （RDW）, man platelet volume （MPV）, patelet hematocrit （PCT）, patelet volume distribution width （PDW）were measured in 187 patients with acute cerebral infarction and 50 cases were as the healthy control. Results ： Most of the traditional Chinese medicine in acute cerebral infarction patients were Qi deficiency and blood stasis group 111 cases（ 59.4% ）, phlegm and blood stasis group 68 cases（ 36.4% ）, hyperactivity of liver Yang and disturbance of wide and fire group 8 eases（4.2% ）. The RDW was statistically significant between Qi deficiency and blood stasis group, hyperactivity of liver Yang and disturbance of wide and fire group and healthy control（ P 〈 0. 05 ） while Qi deficiency and blood stasis group and hyperactivity of liver Yang and disturbance of wide and fire group were significantly different. The Qi deficiency and blood stasis group, phlegm and blood stasis group＇s MPV levels were significantly higher than those of in the control group （ P 〈 0.05 ）. Conclusion： Clinical applications of RDW and MPV in patients with acute cerebral infarction is very wide, simple and has less cost, so RDW and MPV are easily spreaded at the basic - level hospitals. It provides pathophysiological basis for further exploring the integrative medicine diagnosis and treatment of cerebral infarction. |
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| Keywords: | acute cerebral infarction syndrome type of traditional Chinese medicine red blood cell and platelet parameters |
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