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清心安神丸质量标准研究
引用本文:杨琳,王海峰,张红,党秋萍.清心安神丸质量标准研究[J].陕西中医,2020,0(2):258-260,265.
作者姓名:杨琳  王海峰  张红  党秋萍
作者单位:陕西省杨凌示范区医院 杨凌712100;武警陕西总队医院 西安710054;陕西省中医药研究院 西安710003
摘    要:目的:建立清心安神丸的质量标准。方法:通过薄层色谱法定性鉴别该复方制剂中的黄连、川芎、栀子3味药材,采用高效液相色谱法测定清心安神丸中栀子苷的含量。结果:黄连、川芎、栀子薄层鉴别图斑点清晰、重现性好; 栀子苷加样回收率、精密度、稳定性、重现性均良好。结论:本研究建立的检测方法简便、结果准确可靠,可作为清心安神丸制剂的质量控制标准。

关 键 词:清心安神丸  质量标准  黄连  川芎  栀子苷  薄层色谱法  高效液相色谱法

Study on the quality standard of Qingxin Anshen pills
YANG Lin,WANG Haifeng,ZHANG Hong,et al..Study on the quality standard of Qingxin Anshen pills[J].Shaanxi Journal of Traditional Chinese Medicine,2020,0(2):258-260,265.
Authors:YANG Lin  WANG Haifeng  ZHANG Hong  
Affiliation:Department of Pharmacy,Yangling Demonstration Zone Hospital(Yangling 712100)
Abstract:Objective:To establish the quality standard of Qingxin Anshen pills.Methods:Rhizoma coptidis,Rhizoma Chuanxiong and Gardenia in the preparation were identified by TLC.The content of Geniposide in Qingxin Anshen pills was determined by HPLC.Results:TLC identification of Rhizoma coptidis,Rhizoma Chuanxiong and Gardenia’s spots were clear and repeatable.The recovery,precision,stability and reproducibility of gardenoside addition were good.Conclusion:The established method is simple,accurate and reliable,which can be used as the quality control standard of Qingxin Anshen pills.
Keywords:Qingxin Anshen pills  Quality standard  Rhizoma coptidis  Rhizoma chuanxiong  Geniposide  TLC  HPLC
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