| 天晴甘美对慢性乙型肝炎患者外周血单个核细胞细胞周期的影响简 |
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| 引用本文： | 李永伟,柯千山,杨跃武,王拥泽,卢建溪.天晴甘美对慢性乙型肝炎患者外周血单个核细胞细胞周期的影响简[J].亚太传统医药,2013(11):188-190. |
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| 作者姓名： | 李永伟 柯千山 杨跃武 王拥泽 卢建溪 |
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| 作者单位： | [1]中山大学附属第三医院中医科,广东广州510630 [2]中山大学疫苗研究所,广东广州510630 |
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| 基金项目： | 广东省中医药局课题（2010102,20111159） |
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| 摘 要： | 目的：研究天晴甘关注射液对慢性乙型肝炎（慢乙肝）患者外周血单个核细胞（PBMC）细胞周期的影响。方法：采用凯基细胞周期检测法检测天晴甘关对细胞周期的影响。结果：天晴甘美注射液呈剂量依赖性抑制外周血单个核细胞z增殖，使细胞阻滞于G。／G。期，细胞DNA合成减少，但细胞无凋亡。结论：天晴甘美注射液对PBMC具有一定抑制作用，可能使细胞阻滞于G。／G。期，导致细胞DNA合成减少。
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| 关 键 词： | 天晴甘关注射液 慢性乙型肝炎 外周血单个核细胞（PBMC） 细胞周期 |
Inhibitory Effects of Tanqingganmei Injection on PBMC Cells |
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| -Li Yong wei,Ke Qianshan,Yang Yuewu,Wang Yongze,Lu Jianxi.Inhibitory Effects of Tanqingganmei Injection on PBMC Cells[J].Asia-Pacific Traditional Medicine,2013(11):188-190. |
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| Authors: | -Li Yong wei Ke Qianshan Yang Yuewu Wang Yongze Lu Jianxi |
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| Affiliation: | 1. The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou 510630, China; 2. Vaccine Research Institute of Sun Yat-sen University, Guangzhou 510630, China) |
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| Abstract: | Objective.To study cell cycle and inhibitory effects of Tanqingganmei injection on peripheral blood mononuclear cell （PBMC）. Methods. To study effects of Tanqingganmei injection on cell cycle in human peripheral blood mononuelear celI（PBMC）. Results. Tanqingganmei injection inhibited proliferation of PBMC in dose-dependent manner. The cells were inhibited in G0/G1 stage. The number of cells in DNA synthesis phase were reduced, but apoptosis of cells was not shown. Conclusion ： Tanqingganmei injection can inhibit PBMC,which maybe due to retarding PBMC. |
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| Keywords: | Tanqingganmei injection PBMC Cell cycle |
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