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| 狗肝菜保肝作用有效部位筛选研究 | |
| 引用本文： | 张可锋,朱华,高雅.狗肝菜保肝作用有效部位筛选研究[J].中国中药杂志,2010,35(4):497-498. |
| 作者姓名： | 张可锋 朱华 高雅 |
| 作者单位： | 1. 桂林医学院,广西,桂林,541004 2. 桂林医学院,广西,桂林,541004;广西中医学院,广西,南宁,530001 3. 广西中医学院,广西,南宁,530001 |
| 基金项目： | 国家自然科学基金项目(30860393) |
| 摘 要： | 目的:初步确定狗肝菜保肝护肝的有效活性部位.方法:用CCl4制备小鼠急性肝损伤模型,对4个不同极性部位萃取物进行药效学筛选.结果:狗肝菜正丁醇萃取物和水萃取物可明显抑制急性肝损伤小鼠血清中ALT,AST和MDA活性(P＜0.01,P＜0.05),升高SOD活性(P＜0.05).结论:正丁醇部位和水部位为狗肝菜保肝的药效学活性部位. |
| 关 键 词： | 狗肝菜 保肝护肝 活性部位 |
| 收稿时间： | 2009/1/22 0:00:00 |
Research on active extracts of Dicliptera chinensis on liver protection |
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| ZHANG Kefeng,ZHU Hua and GAO Ya.Research on active extracts of Dicliptera chinensis on liver protection[J].China Journal of Chinese Materia Medica,2010,35(4):497-498. | |
| Authors: | ZHANG Kefeng ZHU Hua and GAO Ya |
| Affiliation: | Guilin Medical University,Guilin 541004, China;Guilin Medical University,Guilin 541004, China;Guangxi University of traditional Chinese Medicine, Nanning 530001, China;Guangxi University of traditional Chinese Medicine, Nanning 530001, China |
| Abstract: | Objective: To search pharmacody namic active extracts of Dicliptera chinensis for protecting liver. Method: Rats cute liver injury model was induced by CCl4 to screen the liver protection of four different fraction extracted from an ethanol extract of D. chinensis. Result: The n-butanol fraction and water fraction can prevent the increase of the ALT, AST and MDA(P<0.01,P<0.05), and increase the SOD compared to the normal groups(P<0.05) . Conclusion: The results show that the pharmacody namic active extracts of D. chinensis are the n-butanol and water fractions. |
| Keywords: | Dicliptera chinensis protecting liver active parts |
| 本文献已被 CNKI 万方数据 等数据库收录！ | |
