| 生脉注射液中皂苷类化学成分的研究 |
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| 引用本文： | 汪祺,郑笑为,于健东,刘燕,戴忠,鲁静,林瑞超.生脉注射液中皂苷类化学成分的研究[J].中国中药杂志,2013,38(11):1731-1734. |
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| 作者姓名： | 汪祺 郑笑为 于健东 刘燕 戴忠 鲁静 林瑞超 |
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| 作者单位： | 中国食品药品检定研究院,北京,100050 |
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| 摘 要： | 目的:研究生脉注射液中皂苷类化学成分.方法:采用液相色谱-质谱联用技术对8家生产企业的生脉注射液样品及红参中间体进行化学成分指认.结果:生脉注射液主要色谱峰为红参中皂苷类成分,实验证明有20个皂苷类成分为8家生产企业及红参中间体共有成分.结论:建立了生脉注射液中皂苷类成分的检查方法,为研究注射剂物质基础提供实验依据.
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| 关 键 词： | 生脉注射液 红参 离子阱质谱 皂苷 |
| 收稿时间： | 2011/12/22 0:00:00 |
Study on saponins in Shengmai injection |
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| WANG Qi,ZHENG Xiao-wei,YU Jian-dong,LIU Yan,DAI Zhong,LU Jing and LIN Rui-chao.Study on saponins in Shengmai injection[J].China Journal of Chinese Materia Medica,2013,38(11):1731-1734. |
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| Authors: | WANG Qi ZHENG Xiao-wei YU Jian-dong LIU Yan DAI Zhong LU Jing and LIN Rui-chao |
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| Affiliation: | National Institutes for Food and Drug Control, Beijing 100050, China;National Institutes for Food and Drug Control, Beijing 100050, China;National Institutes for Food and Drug Control, Beijing 100050, China;National Institutes for Food and Drug Control, Beijing 100050, China;National Institutes for Food and Drug Control, Beijing 100050, China;National Institutes for Food and Drug Control, Beijing 100050, China;National Institutes for Food and Drug Control, Beijing 100050, China |
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| Abstract: | Objective: To investigate the saponin in Shengmai injection. Method: On the basic of studing the chemical constituents of red ginseng and Shengmai injection, 20 compositions had been identifided by LC-MS/MS. Result: Twenty identifided compositions were the common components of Shengmai injection and red ginseng extracts. Conclusion: The analytical method for saponins in Shengmai injection was established which could be used as the basis for further study and quality control. |
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| Keywords: | Shengmai injection red ginseng ion trap LC/MS saponin |
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