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中医药干预血管性认知障碍的研究进展
引用本文:蔡颖颖,蒋卫民.中医药干预血管性认知障碍的研究进展[J].中国中药杂志,2017,42(10):1837-1841.
作者姓名:蔡颖颖  蒋卫民
作者单位:南京中医药大学 第一临床医学院, 江苏 南京 210000,南京中医药大学 附属医院 心内科, 江苏 南京 210029
基金项目:江苏省科技厅六大人才高峰项目(2014-WSN-014);江苏高校优势学科建设工程项目(PAPD)
摘    要:血管性认知障碍(VCI)是由各种血管因素引起的从轻度认知功能障碍到痴呆的一类综合征。在进展至血管性痴呆之前,早期诊断、早期干预可以预防和延缓VCI的发展,甚至逆转患者的认知功能损害。大量实验及临床研究证实中药单药、有效部位、复方制剂等具有改善血管性认知功能的作用。该文从VCI的概念、发病机制、细胞和分子机制、中医药治疗的研究进展予以综述。

关 键 词:血管性认知障碍  发病机制  细胞和分子机制  中医药治疗
收稿时间:2016/12/26 0:00:00

Research progress of traditional Chinese medicine intervention vascular cognitive impairment
CAI Ying-ying and JIANG Wei-min.Research progress of traditional Chinese medicine intervention vascular cognitive impairment[J].China Journal of Chinese Materia Medica,2017,42(10):1837-1841.
Authors:CAI Ying-ying and JIANG Wei-min
Affiliation:First Clinical Medical College Nanjing University of Chinese Medicine, Nanjing 210000, China and Department of Cardiology, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing 210029, China
Abstract:Vascular cognitive impairment (VCI) is a kind of syndrome from mild cognitive impairment to dementia, which is caused by different vascular factors. It can be prevented and delayed the progress of VCI and even reversed cognitive impairment before it progresses to vascular dementia by early diagnosis and intervention. Many experimental and clinical studies have confirmed that traditional Chinese medicine (TCM) monomer, effective fraction, compound preparation,etc can improve vascular cognitive function. Our paper summarizes the research progress in the concept, pathogenesis, cellular and molecular mechanisms, and TCM treatment of VCI.
Keywords:vascular cognitive impairment  pathogenesis  cellular and molecular mechanisms  traditional Chinese medicine treatment
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