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| 石蒜鳞茎中的生物碱成分研究 | |
| 引用本文： | 刘霞妹,王磊,殷志琦,张声源,欧阳胜,叶文才.石蒜鳞茎中的生物碱成分研究[J].中国中药杂志,2013,38(8):1188-1192. |
| 作者姓名： | 刘霞妹 王磊 殷志琦 张声源 欧阳胜 叶文才 |
| 作者单位： | 1. 暨南大学药学院中药及天然药物研究所,广东广州,510632 2. 中国药科大学天然药物化学教研室,江苏南京,210009 3. 江西中医学院药学院中药化学教研室,江西南昌,330004 |
| 基金项目： | 国家自然科学基金项目(81273391); 暨南大学科研培育与创新基金项目(21612449) |
| 摘 要： | 采用多种色谱技术,从石蒜鳞茎中分离鉴定了10个生物碱类成分.运用IR,UV,CD,MS,NMR等波谱分析方法鉴定了化合物的结构,分别为oxovittatine(1),apohaemanthamine(2),9-O-demethylhomolycorine N-oxide (3),incartine(4),ismine(5),6-O-methylpretazettine(6),多花水仙碱(7),恩其明(8),高石蒜碱(9)和甲基石蒜伦碱(10).其中化合物1为新的天然产物,化合物2～3为首次从石蒜属植物中分离得到,化合物4～6为首次从该植物中分离得到. |
| 关 键 词： | 石蒜 化学成分 生物碱 |
| 收稿时间： | 2012/12/18 0:00:00 |
Alkaloids from bulbs of Lycoris radiata |
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| LIU Xia-mei,WANG Lei,YIN Zhi-qi,ZHANG Sheng-yuan,OUYANG Sheng and YE Wen-cai.Alkaloids from bulbs of Lycoris radiata[J].China Journal of Chinese Materia Medica,2013,38(8):1188-1192. | |
| Authors: | LIU Xia-mei WANG Lei YIN Zhi-qi ZHANG Sheng-yuan OUYANG Sheng and YE Wen-cai |
| Affiliation: | Institute of Traditional Chinese Medicine and Natural Products, Jinan University, Guangzhou 510632, China;Institute of Traditional Chinese Medicine and Natural Products, Jinan University, Guangzhou 510632, China;Department of Natural Medicinal Chemistry, China Pharmaceutical University, Nanjing 210009, China;Institute of Traditional Chinese Medicine and Natural Products, Jinan University, Guangzhou 510632, China;College of Pharmacy, JiangXi University of Traditional Chinese Medicine, Nanchang 330004, China;Institute of Traditional Chinese Medicine and Natural Products, Jinan University, Guangzhou 510632, China |
| Abstract: | Ten Amaryllidaceae alkaloids were isolated from the bulbs of Lycoris radiata. Their structures were identified as oxovittatine (1), apohaemanthamine (2), 9-O-demethylhomolycorine N-oxide (3), incartine (4), ismine (5), 6-O-methylpretazettine (6), tazettine (7), ungeremine (8), homolycorine (9), and O-methyllycorenine (10) by spectroscopic data analyses. Compound 1 was a new natural product. Compounds 2 and 3 were reported form the genus Lycoris for the first time and compounds 4-6 were isolated form the title plant for the first time. |
| Keywords: | Lycoris radiata chemical constituent alkaloids |
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