| D301树脂吸附丹参有效成分的研究 |
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| 引用本文： | 王志平,范晋勇,刘玉强,元英进.D301树脂吸附丹参有效成分的研究[J].中国中药杂志,2004,29(9):854-857. |
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| 作者姓名： | 王志平 范晋勇 刘玉强 元英进 |
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| 作者单位： | 天津大学,制药工程系,天津,300072 |
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| 摘 要： | 目的 :考察利用大孔树脂D301,富集丹参水提取液中有效成分丹参素及原儿茶醛 ,去除杂质 ,降低出膏率 ,提高膏中有效成分含量。方法 :以丹参素 ,原儿茶醛为指标 ,HPLC检测分离前后有效成分的含量变化。结果 :D301树脂能够有效的吸附丹参素和原儿茶醛。结论 :采用D301树脂可以作为改进分离纯化工艺 ,去除杂质 ,提高粗提物中有效成分含量。
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| 关 键 词： | 大孔树脂 丹参素 原儿茶醛 HPLC |
| 文章编号： | 1001-5302(2004)09-0854-04 |
| 收稿时间： | 2003/4/20 0:00:00 |
Study on adsorption of Danshen water-soluble compounds with macroporous resin D301 |
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| WANG Zhi-ping;FAN Jin-yong;LIU Yu-qiang;YUAN Ying-jin.Study on adsorption of Danshen water-soluble compounds with macroporous resin D301[J].China Journal of Chinese Materia Medica,2004,29(9):854-857. |
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| Authors: | WANG Zhi-ping;FAN Jin-yong;LIU Yu-qiang;YUAN Ying-jin |
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| Affiliation: | Department of Pharmaceutical Engineering, School of Chemical Engineering and Technology, Tianjin University, Tianjin 300072, China. gregorywang@eyou.com |
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| Abstract: | Objective: To study the adsorption and en ri chment of effective compounds of danshensu, and protocatechualdehyde from Danshe n water extracts by macroporous resin D301. Method: The ch ange of active compounds was observed by detecting the amount of danshensu and p rotocatechualdehyde with HPLC. Result and Conclusion: Macr oporous resins D301 can be used in the process of adsorbing and purifying active compounds of danshensu and protocatechualdehyde, and increase the amount of act ive compounds in water extracts. |
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| Keywords: | macroporous resin danshensu protocatech ualdehyde HPLC |
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