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Phytochemistry, Metabolism, and Metabolomics of Ginseng |
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| Authors: | Xiao-peng Chen Yan-ping Lin Yao-zhong Hu Chang-xiao Liu Ke Lan and Wei Jia |
| Affiliation: | 1. Department of Molecular Biosciences,School of Veterinary Medicine,University of California,Davis,CA 95616,USA;Tasly Academy,Tasly Holding Group,Tianjin 300410,China 2. Department of Molecular Biosciences,School of Veterinary Medicine,University of California,Davis,CA 95616,USA 3. Laboratory of Cellular and Molecular Immunology,Vrije Universiteit Brussel,Brussel B-1050s,Belgium;School of Chemical Engineering and Technology,Tianjin University,Tianjin 300072,China 4. State Key Laboratory of Drug Delivery Technology and Pharmacokinetics,Tianjin 300193,China 5. Cancer Epidemiology,University of Hawaii Cancer Center,Honolulu,HI 96813,USA |
| Abstract: | Ginseng, as a medicinal plant, has been used for thousands of years in China, Korea, and Japan, and the study on ginseng is a hotspot in the research field as evidenced by about 7000 scientific papers in PUBMED. In recent decades, many ginseng studies focused on the metabolism and metabolomics of ginseng or its active ingredients using modern bioanalytical technologies. To date, more than 200 ginsenosides and non-saponin constituents have been isolated and identified. In the past decades, rapid development of analytical technologies has facilitated the advancement of ginseng research in many ways. In this review, we focus on the advances of ginseng research in chemistry, pharmacology, and metabolomics. We also provide the comments on the significance as well as challenges of metabolomics-based ginseng studies. |
| Keywords: | ginseng ginsenoside herbal medicines metabolomics metabonomics pharmacology traditional Chinese medicines |
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