| 南药巴戟天的化学成分 |
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| 引用本文： | 张海龙,张庆文,张晓琦,叶文才,王一涛.南药巴戟天的化学成分[J].中国天然药物,2010(3):192-195. |
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| 作者姓名： | 张海龙 张庆文 张晓琦 叶文才 王一涛 |
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| 作者单位： | 澳门大学中华医药研究院;暨南大学中药及天然药物研究所;暨南大学中药药效物质基础及创新药物研究广东省重点实验室;中国药科大学天然药物教研室; |
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| 基金项目： | supported by grants from Macao Science and Technology Development Fund(013/2008/A1); the Team Project of the Natural Science Foundation of Guangdong(No.8351063201000003)~~ |
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| 摘 要： | 目的：研究南药巴戟天Morinda officinalis How的化学成分。方法：利用硅胶柱层析和凝胶柱层析对南药巴戟天的根茎进行分离纯化,利用光谱学手段鉴定其结构。结果：分离得到17个已知化合物：大黄素甲醚（1）,1-羟基-2-甲基蒽醌（2）,2-羟基-1-甲氧基蒽醌（3）,甲基异茜草素（4）,甲基异茜草素1-甲醚（5）,1,3-二羟基-2-甲氧基蒽醌（6）,3-羟基-2-甲基蒽醌（7）,Digiferruginol（8）,1,2-二甲氧基-3-羟基蒽醌（9）,1,3-二羟基-2-羟甲基蒽醌（10）,光泽汀ω-乙醚（11）,蒽醌-2-羧酸（12）,7-羟基-6-甲氧基香豆素（13）,反式丁烯二酸（14）,豆甾醇（15）,胡萝卜苷（16）和β-谷甾醇（17）。结论：化合物8-12,14-16首次从该植物中分离得到,并且化合物12和14首次从巴戟天属植物中分离。
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| 关 键 词： | 巴戟天 化学成分 蒽醌 |
Chemical Constituents from the Roots of Morinda officinalis |
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| ZHANG Hai-Long,ZHANG Qing-Wen,ZHANG Xiao-Qi,YE Wen-Cai,WANG Yi-TaoInstitute of Chinese Medical Sciences,University of Macau,Macau.Chemical Constituents from the Roots of Morinda officinalis[J].Chinese JOurnal of Natural Medicines,2010(3):192-195. |
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| Authors: | ZHANG Hai-Long ZHANG Qing-Wen ZHANG Xiao-Qi YE Wen-Cai WANG Yi-TaoInstitute of Chinese Medical Sciences University of Macau Macau |
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| Affiliation: | ZHANG Hai-Long1,ZHANG Qing-Wen1*,ZHANG Xiao-Qi2,3,YE Wen-Cai2,4,WANG Yi-Tao11Institute of Chinese Medical Sciences,University of Macau,Macau,2Institute of Traditional Chinese Medicine , Natural Products,College of Pharmacy,Jinan University,Guangzhou,510632,3Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM , New Drugs Research,Guangzhou 510632,4Department of Natural Medicinal Chemistry,China Pharmaceutical University,Nanjing,210009,China |
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| Abstract: | AIM:To investigate the chemical constituents from the roots of Morinda officinalis.METHODS:The chemical constituents were isolated by column chromatography using silica gel and Sephadex LH-20,and their structures were elucidated on the basis of spectroscopic analysis.RESULTS:Seventeen compounds were identified as physcion(1),1-hydroxy-2-methylanthraquinone(2),2-hydroxy-1-methoxyanthraquinone(3),rubiadin(4),rubiadin 1-methylether(5),1,3-dihydroxy-2-methoxyanthraquinone(6),3-hydroxy-2-methylanthraquinone(7),d... |
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| Keywords: | Morinda officinalis Chemical constituents Anthraquinone |
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