雷公藤多甙治疗激素依赖型阿斯匹林性哮喘36例

３６例自身对照以雷公藤多甙片每日６０ｍｇ，分３次口服，替代皮质激素治疗激素依赖型阿斯匹林性哮喘。结果显示：显效３１例（８６．１１％）有效５例（１３．８９％），总有效率１００％。治疗后血总皮质醇上升达正常范围（Ｐ＜０．００１），柯兴氏综合征逐渐消失，９例合并糖尿病者血糖正常，尿糖阴性。治疗后最大呼气流量值有不同程度上升（男Ｐ＜０．０１，女Ｐ＜０．０５），无合并肺气肿者上升幅度较大，合并肺气肿者上升幅

Treatment of 36 Corticosteroid-Dependent Type of Aspirin Asthma Patients with

This paper reports that substitution of Glucosidorum Tripterygii Totorum(GTT) for cortical hormone used to treat corticosteroid-dependent type of aspirin asthma, 60 mg, 3 times a day. The result showed that total effective rate was 100% including 31 cases of marked effective(86.11%) and 5 cases of effective (13.89%). Corticosteriod in the blood was significantly elevated to normal level after treatment(P<0.001), Cushing's syndrome was cleared up gradually. The blood glucose in 9 cases complicated with diabetes mellitus was recovered and glucosuria test was negative. The value of peak expiratory flow(PEF) was increased to some extent(P of male<0.01, of female<0.05),especially on those not complicated with emphysema. There was no side-effect during the treatment and could avoid the side-effect of cortical hormone. This therapy was valuable.