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针刺干预抑郁的临床评价与中枢机制研究进展
引用本文:余云进,冯军,张荣,唐纯志,史亚飞.针刺干预抑郁的临床评价与中枢机制研究进展[J].上海针灸杂志,2019(3):349-354.
作者姓名:余云进  冯军  张荣  唐纯志  史亚飞
作者单位:广州中医药大学深圳医院;广州中医药大学
基金项目:国家自然科学基金项目(81573912);深圳市福田区公益科技项目(FTW2015003);广州中医药大学高水平大学建设资助项目(A1-AFD018171Z11032)
摘    要:回顾了近10余年来在国际期刊发表的针刺干预抑郁症的相关研究文献,探讨针刺治疗抑郁的临床和机制研究中所取得的成果与发展方向。资料显示,针刺干预抑郁具有肯定的疗效与独特的优势,针刺干预抑郁症的研究在近些年取得了重要进展,尤其是在HPA轴、神经递质、信号通路、炎症反应和基因表达等方面。但具体机制尚不清楚,针刺对抑郁的研究有待进一步完善。

关 键 词:针刺疗法  电针  抑郁  综述  研究进展

Research Advances in the Clinical Assessment of Acupuncture Intervention in Depression and the Central Mechanism
YU Yun-jin,FENG Jun,ZHANG Rong,TANG Chun-zhi,SHI Ya-fei.Research Advances in the Clinical Assessment of Acupuncture Intervention in Depression and the Central Mechanism[J].Shanghai Journal of Acupuncture and Moxibustion,2019(3):349-354.
Authors:YU Yun-jin  FENG Jun  ZHANG Rong  TANG Chun-zhi  SHI Ya-fei
Affiliation:(Guangzhou University of Traditional Chinese Medicine Shenzhen Hospital,Shenzhen 518033,China;Guangzhou University of Traditional Chinese Medicine,Guangzhou 510006,China)
Abstract:This article reviews related research literature on acupuncture intervention in depression published in international journals in recent more than 10 years and explore achievements in and the development direction of clinical and mechanism studies on acupuncture treatment for depression. The data show that acupuncture has a definite therapeutic effect and unique advantage in its intervention in depression. In recent years, studies on acupuncture intervention in depression made important progress, especially in the HPA axis, neurotransmitters, signaling pathways, inflammatory reactions and gene expressions. But the specific mechanisms are still unclear. Studies on acupuncture for depression remain to be further improved.
Keywords:Acupuncture therapy  Electroacupuncture  Depression  Review  Research advance
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