重灸中脘穴对脾胃虚寒型糖尿病胃轻瘫患者胃肠激素、胃动力学的影响

目的观察重灸中脘穴对脾胃虚寒型2型糖尿病胃轻瘫患者胃肠激素、胃动力学的影响。方法选取符合纳入标准的88例脾胃虚寒型糖尿病胃轻瘫患者,按随机数字表法分为治疗组和对照组,每组44例。对照组采用常规药物治疗,治疗组采用重灸中脘穴治疗。疗程结束后记录并对比分析两组临床疗效、胃肠激素胃泌素(GAS)、胃动素(MTL)]、胃动力学(胃收缩频率、胃排空时间、胃排空率)、主要临床症状评分等变化。结果治疗组临床疗效明显优于对照组,差异具有统计学意义(P<0.05);两组治疗后GAS、MTL均明显优于治疗前(P<0.05),且治疗组明显优于对照组(P<0.05);两组治疗后胃收缩频率、胃排空时间、胃排空率均明显优于治疗前(P<0.05),且治疗组明显优于对照组(P<0.05);两组治疗后主要临床症状评分均明显优于治疗前(P<0.05),且治疗组明显优于对照组(P<0.05)。结论在常规药物治疗基础上重灸中脘穴治疗脾胃虚寒型2型糖尿病胃轻瘫,可调节胃肠激素,改善胃肠动力,促进胃肠功能恢复。

Effects of Large-dose Moxibustion at Zhongwan(CV12)on Gastrointestinal Hormones and Gastric Motility in Patients with Diabetic Gastroparesis Due to Deficient Cold of Spleen and Stomach

Objective To observe the effects of large-dose moxibustion at Zhongwan(CV12)on gastrointestinal hormones and gastric motility in type 2 diabetic patients with gastroparesis due to deficient cold of spleen and stomach.Method Eighty-eight eligible patients with diabetic gastroparesis due to deficient cold of spleen and stomach were divided into a treatment group and a control group by random number table method,with 44 cases in each group.The control group was intervened by conventional medications,while the treatment group was intervened by large-dose moxibustion at Zhongwan.At the end of intervention,the clinical efficacies were recorded and comparatively analyzed,as well as the levels of gastrointestinal hormonesgastrin(GAS)and motilin(MTL)]and gastric motility(gastric contraction frequency,gastric emptying time and gastric emptying rate),and main clinical symptom scores.Result The clinical efficacy was obviously better in the treatment group than in the control group with statistical significance(P<0.05).After treatment,the GAS and MTL were significantly improved in both groups(P<0.05),and were significantly better in the treatment group than in the control group(P<0.05).The gastric contraction frequency,gastric emptying time and gastric emptying rate were significantly improved after treatment in the two groups(P<0.05),and were significantly better in the treatment group than in the control group(P<0.05).The main clinical symptom scores showed significant improvements after treatment in the two groups(P<0.05),and were significantly better in the treatment group than in the control group(P<0.05).Conclusion Based on the conventional medication treatment,large-dose moxibustion at Zhongwan can regulate the gastrointestinal hormones,improve gastric motility and boost the recovery of gastrointestinal function in the treatment of gastroparesis in type 2 diabetes due to deficient cold of spleen and stomach.