动脉硬化性脑梗死患者中医证候分布规律研究

目的探讨动脉硬化性脑梗死患者证候要素组合与分布规律。方法通过临床流行病学横断面调查获取417例动脉硬化性脑梗死患者四诊资料,以基于熵的复杂系统分划方法提取证候要素,确定症状贡献度,建立诊断阈值,通过阈值辨证结果,分析本病证候要素组合与分布规律。结果动脉硬化性脑梗死存在气虚、气滞、血瘀、痰浊、郁热、痰热、阴虚、阳虚等证候要素,可有单一证候要素、2个证候要素、3个证候要素及4个或以上证候要素组合类型,气虚、气滞、血瘀、痰浊在本病证候要素总体分布及组合分布中出现频率较高。结论动脉硬化性脑梗死病机复杂,其主要病机特点为气虚为本,气滞、血瘀、痰浊为标,临床应全面分析。

The Research of Distribution Regularity on TCM Syndrome of Atherosclerotic Infarct of Brain Patients

Objective:To explore the regularity of combination and distribution of TCM syndrome element in syndrome of atherosclerotic infarct of brain patients.Methods:We Obtain the data of 417 case of atheroselerotic infarct of brain patients by the method of clinical epidemic cross-sectional study,and the extraction of syndrome element,contribution of symptoms to syndrome and diagnostic threshold were completed by Entropy-based Complex Systems Partition.According to the result of the quantixation diagnostic criteria of syndrome,the regularity of combinaton and distribution of syndrome element in the disease was analyzed.Results:The disease of atherosclerotic infarct of brain has the basic syndromes,such as Qi Deficiency syndrome,Qi Stagnation syndrome,Blood Stasis syndrome,Phlegm and Damp syndrome,Phlegm-fire syndrome,Stagnation-fire syndrome,Yin Deficiency syndrome and Yang Deficiency syndrome.It showed the combination types of 1 syndrome,2 syndromes,3 syndromes or 4 and above syndromes.Qi Deficiency syndrome,Qi Stagnation syndrome,Blood Stasis syndrome,Phlegm and Damp syndrome had the higher frequency in atherosclerotic infarct of brain patients.Conclusion:The disease of atherosclerotic infarct of brain had the complicated pathogenesis.Qi Deficiency syndrome,Qi Stagnation syndrome,Blood Stasis syndrome,Phlegm and Damp syndrome were the main pathogenesis elements.Overall analysis should be done before diagnosis.