| 肠道菌群与中药相互作用的研究进展 |
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| 引用本文： | 汤齐,高霞,耿婷,黄文哲,刘丽芳,王振中.肠道菌群与中药相互作用的研究进展[J].中草药,2017,48(17):3629-3635. |
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| 作者姓名： | 汤齐 高霞 耿婷 黄文哲 刘丽芳 王振中 |
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| 作者单位： | 中国药科大学, 江苏 南京 210038;江苏康缘药业股份有限公司, 江苏 连云港 222001;中药制药过程新技术国家重点实验室, 江苏 连云港 222001;江苏康缘药业股份有限公司, 江苏 连云港 222001;中药制药过程新技术国家重点实验室, 江苏 连云港 222001;江苏康缘药业股份有限公司, 江苏 连云港 222001;中药制药过程新技术国家重点实验室, 江苏 连云港 222001;江苏康缘药业股份有限公司, 江苏 连云港 222001;中药制药过程新技术国家重点实验室, 江苏 连云港 222001;中国药科大学, 江苏 南京 210038;江苏康缘药业股份有限公司, 江苏 连云港 222001;中药制药过程新技术国家重点实验室, 江苏 连云港 222001 |
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| 基金项目： | 科技部重大新药创制：现代中药创新集群与数字制药技术平台（2013ZX09402203） |
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| 摘 要： | 肠道菌群作为人体内庞大的微生态系统,与人体健康状况有着密切的关联。其特点是数量大、种类多,一旦失调,将会引发各种疾病。中药对肠道菌群的稳态具有调节作用,同时肠道菌群对中药成分具有代谢转化作用,中药与肠道菌群的相互作用研究对实现中药现代化具有重要意义。对近年来关于肠道菌群与中药相互作用的研究成果进行整理归纳,为后续进一步深入研究中药与肠道菌群的关系提供参考。
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| 关 键 词： | 肠道菌群 中药 相互作用 微生态系统 代谢综合征 |
| 收稿时间： | 2017/4/6 0:00:00 |
Research progress on intestinal flora interact with Chinese materia medica |
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| TANG Qi,GAO Xi,GENG Ting,HUANG Wen-zhe,LIU Li-fang and WANG Zhen-zhong.Research progress on intestinal flora interact with Chinese materia medica[J].Chinese Traditional and Herbal Drugs,2017,48(17):3629-3635. |
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| Authors: | TANG Qi GAO Xi GENG Ting HUANG Wen-zhe LIU Li-fang and WANG Zhen-zhong |
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| Affiliation: | China Pharmaceutical University, Nanjing 210038, China;Jiangsu Kanion Pharmarceutical Co., Ltd., Lianyungang 222001, China;State Key Laboratory of New-tech for Chinese Medicine Pharmaceutical Process, Lianyungang 222001, China;Jiangsu Kanion Pharmarceutical Co., Ltd., Lianyungang 222001, China;State Key Laboratory of New-tech for Chinese Medicine Pharmaceutical Process, Lianyungang 222001, China;Jiangsu Kanion Pharmarceutical Co., Ltd., Lianyungang 222001, China;State Key Laboratory of New-tech for Chinese Medicine Pharmaceutical Process, Lianyungang 222001, China;Jiangsu Kanion Pharmarceutical Co., Ltd., Lianyungang 222001, China;State Key Laboratory of New-tech for Chinese Medicine Pharmaceutical Process, Lianyungang 222001, China;China Pharmaceutical University, Nanjing 210038, China;Jiangsu Kanion Pharmarceutical Co., Ltd., Lianyungang 222001, China;State Key Laboratory of New-tech for Chinese Medicine Pharmaceutical Process, Lianyungang 222001, China |
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| Abstract: | There are a huge number of microorganisms in human intestinal, and they are closely related to human health. Their characteristics are huge amount and great variety, if the intestinal flora are imbalance, it could cause a variety of diseases. Traditional Chinese medicine can balance the intestinal flora, meanwhile intestinal flora can metabolize Chinese materia medica (CMM) to effective component. The research on CMM and the intestinal flora has great significance to realize the modernization of CMM. In this paper, we summarized the recent years'' research reports and its achievements on the interaction of intestinal flora and CMM, and provide a reference for further research about the relationship of intestinal flora and CMM. |
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| Keywords: | intestinal flora Chinese materia medica interaction microecosystem metabolic syndrome |
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