多指标决策分析TOPSIS对三七的质量评价研究

目的以多个指标对三七Panax notoginseng进行优质种源筛选,提高三七的整体质量评价水平。方法通过测定云南省12个产地三七样品中三七皂苷R1、人参皂苷Rg1、人参皂苷Re、人参皂苷Rb1、总黄酮和总多糖的量,结合逼近理想解排序法(TOPSIS)建立整体质量评价模型。结果文山、红河、玉溪、昆明和曲靖三七样品与最优方案接近程度Ci的平均值分别为0.300 2、0.341 1、0.279 5、0.338 7与0.323 0,表明云南不同产地三七的整体质量较为接近,道地产地文山与其余产地三七的整体质量差别较小。样品编号为S46、S16及S33的Ci值在所有样品中排名前3,表明这3个样品的整体质量较高,可作为优质种源进一步开发利用。结论熵权TOPSIS模型排除了人为因素的干扰,并将多维问题转化为一维问题,提高了多指标决策分析的科学性与准确性,可对三七进行整体质量评价及优质种源筛选。该方法理论完善、易于操作,可推广于其他中药的相关研究,为保证中药安全、稳定及有效提供研究基础。

Multiple attribute decision making analysis TOPSIS on quality evaluation study of Panax notoginseng

Objective The selection of excellent provenances by using multi-index test can improve the overall quality and stability of Panax notoginseng. Methods In this study, Panax notoginseng samples were collected from 12 sites in Yunnan Province. The contents of notoginsenoside R₁, ginsenoside Rg₁, ginsenoside Re, ginsenoside Rb₁, total flavonids and total polysaccharides were determined, and the entire quality evaluation model was established by technique for order preference by similarity to ideal solution (TOPSIS). Results The averaged C_i of samples from Wenshan, Honghe, Yuxi, Kunming, and Qujing were 0.300 2, 0.341 1, 0.279 5, 0.338 7, and 0.323 0, respectively. It was indicated that the overall quality of P. notoginseng from different origins of Yunnan Province was similar, and there were few differences among the overall qualities of samples from Wenshan which was the traditional genuine region of P. notoginsneg and the other ones. The C_i values of S₄₆, S₁₆, and S₃₃ topped the list of all samples, which showed that these three samples have higher overall qualities, and they can be used as the dominant provenances for the further study. Conclusion The model of entropy weight TOPSIS could eliminate the interference of the artificial factors, transform multiple dimension problems into one dimension problem, and increase the scientificity and accuracy of the multi-criteria decision analysis, obviously. It could obtain a better result on the overall quality evaluation and the dominant provenance selection of P. notoginseng. On the other hand, this method is easy to perform and the theory was perfect. It can be also used in the correlative study of other TCMs and provide the research basis in order to ensure the safety, stability and effectiveness of TCMs.