| 银杏内酯注射液的HPLC指纹图谱研究 |
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| 引用本文： | 章晨峰,付小环,毕宇安,尚强,王振中,盛龙生.银杏内酯注射液的HPLC指纹图谱研究[J].中草药,2010,41(10):1637-1639. |
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| 作者姓名： | 章晨峰 付小环 毕宇安 尚强 王振中 盛龙生 |
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| 作者单位： | 中国药科大学，江苏 南京 210009；江苏康缘药业股份有限公司，江苏 连云港 222001;江苏康缘药业股份有限公司，江苏 连云港 222001;中国药科大学，江苏 南京 210009 |
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| 摘 要： | 目的建立银杏内酯注射液的合适质量控制方法。方法采用HPLC/ELSD法,指纹图谱相似度用中药色谱指纹图谱相似度评价系统(版本2004A)计算。结果 10批注射液的指纹图谱相似度均大于0.95,确定了4个共有峰,建立了该注射液的指纹图谱。结论本法可作为银杏内酯注射液的质量控制方法。
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| 关 键 词： | 银杏内酯注射液 指纹图谱 HPLC/ELSD |
| 收稿时间： | 2010/4/15 0:00:00 |
HPLC Fingerprint of Ginkgolide Injection |
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| ZHANG Chen-feng,FU Xiao-huan,BI Yu-an,SHANG Qiang,WANG Zhen-zhong and SHENG Long-sheng.HPLC Fingerprint of Ginkgolide Injection[J].Chinese Traditional and Herbal Drugs,2010,41(10):1637-1639. |
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| Authors: | ZHANG Chen-feng FU Xiao-huan BI Yu-an SHANG Qiang WANG Zhen-zhong and SHENG Long-sheng |
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| Affiliation: | China Pharmaceutical University, Nanjing 210009, China;Jiangsu Kanion Pharmaceutical Co., Ltd., Lianyungang 222001, China;Jiangsu Kanion Pharmaceutical Co., Ltd., Lianyungang 222001, China;Jiangsu Kanion Pharmaceutical Co., Ltd., Lianyungang 222001, China;Jiangsu Kanion Pharmaceutical Co., Ltd., Lianyungang 222001, China;Jiangsu Kanion Pharmaceutical Co., Ltd., Lianyungang 222001, China;China Pharmaceutical University, Nanjing 210009, China |
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| Abstract: | Objective To establish the proper quality control method for Ginkgolide Injection.MethodsThe Ginkgolide Injection was analyzed by using HPLC/ELSD technology.The similarity of fingerprints was calculated by the Similarity Evaluation System for Chromatographic Fingerprint of Chinese Traditional Medicine(Version 2004A).Results Similarity of ten batches of injections was all over 0.95.The fingerprint for Ginkgolide Injection was established and four common peaks were indicated.Conclusion This method is suitable for the quality control of Ginkgolide Injection. |
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| Keywords: | Ginkgolide Injection fingerprint HPLC/ELSD |
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