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雪胆属植物的化学成分及生物活性研究进展
引用本文:李莹,徐晓婷,郑重飞,李玲,姚庆强.雪胆属植物的化学成分及生物活性研究进展[J].中草药,2015,46(18):2800-2808.
作者姓名:李莹  徐晓婷  郑重飞  李玲  姚庆强
作者单位:山东省医学科学院药物研究所, 济南大学 山东省医学科学院医学与生命科学学院, 山东省罕少见病重点实验室, 山东 济南 250062;山东省医学科学院药物研究所, 济南大学 山东省医学科学院医学与生命科学学院, 山东省罕少见病重点实验室, 山东 济南 250062;山东省医学科学院药物研究所, 济南大学 山东省医学科学院医学与生命科学学院, 山东省罕少见病重点实验室, 山东 济南 250062;山东省医学科学院药物研究所, 济南大学 山东省医学科学院医学与生命科学学院, 山东省罕少见病重点实验室, 山东 济南 250062;山东省医学科学院药物研究所, 济南大学 山东省医学科学院医学与生命科学学院, 山东省罕少见病重点实验室, 山东 济南 250062
摘    要:雪胆属植物中含有丰富的三萜皂苷类成分,并且因其具有显著的抗肿瘤和抗菌消炎等生物活性而越来越受到医药领域的关注。近年来,国内外学者对雪胆属植物化学成分、药理活性等方面进行了大量研究,并取得了很大的进展。综述近30年来雪胆属的植物来源、三萜皂苷结构、波谱特征以及生物活性的研究进展,为雪胆属植物的进一步开发利用提供依据。

关 键 词:雪胆属  植物资源  三萜皂苷  抗肿瘤  抗炎
收稿时间:4/3/2015 12:00:00 AM

Research progress on chemical constituents and biological activities of plants from Hemsleya Cogn.
LI Ying,XU Xiao-ting,ZHENG Zhong-fei,LI Ling and YAO Qing-qiang.Research progress on chemical constituents and biological activities of plants from Hemsleya Cogn.[J].Chinese Traditional and Herbal Drugs,2015,46(18):2800-2808.
Authors:LI Ying  XU Xiao-ting  ZHENG Zhong-fei  LI Ling and YAO Qing-qiang
Affiliation:Institute of Materia Medica, Shandong Academy of Medical Sciences, University of Jinan, Shandong Academy of Medical Sciences, School of Medicine and Life Sciences, Key Laboratory of Rare and Uncommon Diseases of Shandong Province, Jinan 250062, China;Institute of Materia Medica, Shandong Academy of Medical Sciences, University of Jinan, Shandong Academy of Medical Sciences, School of Medicine and Life Sciences, Key Laboratory of Rare and Uncommon Diseases of Shandong Province, Jinan 250062, China;Institute of Materia Medica, Shandong Academy of Medical Sciences, University of Jinan, Shandong Academy of Medical Sciences, School of Medicine and Life Sciences, Key Laboratory of Rare and Uncommon Diseases of Shandong Province, Jinan 250062, China;Institute of Materia Medica, Shandong Academy of Medical Sciences, University of Jinan, Shandong Academy of Medical Sciences, School of Medicine and Life Sciences, Key Laboratory of Rare and Uncommon Diseases of Shandong Province, Jinan 250062, China;Institute of Materia Medica, Shandong Academy of Medical Sciences, University of Jinan, Shandong Academy of Medical Sciences, School of Medicine and Life Sciences, Key Laboratory of Rare and Uncommon Diseases of Shandong Province, Jinan 250062, China
Abstract:Plants in genus Hemsleya Cogn. are rich in triterpenoid saponins, and are got more attention for their significant antitumor and anti-inflammatory activity from all walks of life. This paper summarizes the progress of plant sources for nearly 30 years, including chemical constituents, spectral characteristics, and biological activity, and provides the direction for further study.
Keywords:Hemsleya Cogn    plant sources  triterpenoid saponin  antitumor  anti-inflammation
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