| 海洋中药秋茄的化学成分及药理活性研究进展＊ |
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| 引用本文： | 吴秀彩,杜正彩,郝二伟,谢金玲,韦林垚,吴东阳,陈锋,侯小涛,邓家刚.海洋中药秋茄的化学成分及药理活性研究进展＊[J].世界科学技术-中医药现代化,2021,23(12):357-369. |
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| 作者姓名： | 吴秀彩 杜正彩 郝二伟 谢金玲 韦林垚 吴东阳 陈锋 侯小涛 邓家刚 |
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| 作者单位： | 广西中医药大学药学院 南宁 530200;广西中药药效研究重点实验室 南宁 530001;广西农作物废弃物功能成分研究协同创新中心 南宁 530200;广西中医药大学广西中医药科学实验中心 南宁 530200,广西中药药效研究重点实验室 南宁 530001;广西农作物废弃物功能成分研究协同创新中心 南宁 530200;广西中医药大学广西中医药科学实验中心 南宁 530200,广西中药药效研究重点实验室 南宁 530001;广西农作物废弃物功能成分研究协同创新中心 南宁 530200;广西中医药大学广西中医药科学实验中心 南宁 530200,广西中药药效研究重点实验室 南宁 530001;广西农作物废弃物功能成分研究协同创新中心 南宁 530200;广西中医药大学广西中医药科学实验中心 南宁 530200,广西中药药效研究重点实验室 南宁 530001;广西农作物废弃物功能成分研究协同创新中心 南宁 530200;广西中医药大学广西中医药科学实验中心 南宁 530200,广西中药药效研究重点实验室 南宁 530001;广西农作物废弃物功能成分研究协同创新中心 南宁 530200;广西中医药大学广西中医药科学实验中心 南宁 530200,广西中药药效研究重点实验室 南宁 530001;广西农作物废弃物功能成分研究协同创新中心 南宁 530200;广西中医药大学广西中医药科学实验中心 南宁 530200,广西中医药大学药学院 南宁 530200;广西中药药效研究重点实验室 南宁 530001;广西农作物废弃物功能成分研究协同创新中心 南宁 530200;广西中医药大学广西中医药科学实验中心 南宁 530200,广西中药药效研究重点实验室 南宁 530001;广西农作物废弃物功能成分研究协同创新中心 南宁 530200;广西中医药大学广西中医药科学实验中心 南宁 530200 |
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| 基金项目： | 广西壮族自治区科学技术厅广西科技计划基地和人才专项“广西中药药效研究重点实验室建设”项目（17-259-20）：广西中药药效研究重点实验室,负责人：邓家刚。 |
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| 摘 要： | 秋茄（Kandelia candel）属于红树科（Rhizophoraceae）秋茄属（kandelia）,是一种生长于滨海滩涂的海洋植物,在广西沿海地区被民间用作药物使用。其化学成分主要包括黄酮类、萜类、酚酸类、有机酸、甾醇、含氮化合物、多糖等。现代药理研究表明秋茄具有抗肿瘤、抑菌、抗氧化、降血糖和血脂、抗炎等多种药理活性。本文深入总结秋茄的化学成分及药理活性的研究现状,为该海洋中药的临床应用、质量控制和产品开发等提供参考。
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| 关 键 词： | 秋茄 黄酮类 萜类 酚酸类 鞣质 抗肿瘤活性 抗氧化活性 抑菌活性 |
| 收稿时间： | 2021/3/17 0:00:00 |
| 修稿时间： | 2022/2/21 0:00:00 |
Research Progress on Chemical Constituents and Pharmacological Activities of Marine Medicine Kandelia candel |
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| Wu Xiucai,Du Zhengcai,Hao Erwei,Xie Jinling,Wei Linyao,Wu Dongyang,Chen Feng,Hou Xiaotao and Deng Jiagang.Research Progress on Chemical Constituents and Pharmacological Activities of Marine Medicine Kandelia candel[J].World Science and Technology-Modernization of Traditional Chinese Medicine,2021,23(12):357-369. |
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| Authors: | Wu Xiucai Du Zhengcai Hao Erwei Xie Jinling Wei Linyao Wu Dongyang Chen Feng Hou Xiaotao and Deng Jiagang |
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| Affiliation: | Faculty of Pharmacy, Guangxi University of Chinese Medicine, Nanning 530200, China;Guangxi Key Laboratory of Efficacy Study on Chinese Materia Medica, Nanning 530001, China;Guangxi Collaborative Innovation Center of Study on Functional Ingredients of Agricultural Residues, Nanning 530200, China;Guangxi Scientific Experimental Center of Traditional Chinese Medicine, Guangxi University of Chinese Medicine, Nanning 530200, China,Guangxi Key Laboratory of Efficacy Study on Chinese Materia Medica, Nanning 530001, China;Guangxi Collaborative Innovation Center of Study on Functional Ingredients of Agricultural Residues, Nanning 530200, China;Guangxi Scientific Experimental Center of Traditional Chinese Medicine, Guangxi University of Chinese Medicine, Nanning 530200, China,Guangxi Key Laboratory of Efficacy Study on Chinese Materia Medica, Nanning 530001, China;Guangxi Collaborative Innovation Center of Study on Functional Ingredients of Agricultural Residues, Nanning 530200, China;Guangxi Scientific Experimental Center of Traditional Chinese Medicine, Guangxi University of Chinese Medicine, Nanning 530200, China,Guangxi Key Laboratory of Efficacy Study on Chinese Materia Medica, Nanning 530001, China;Guangxi Collaborative Innovation Center of Study on Functional Ingredients of Agricultural Residues, Nanning 530200, China;Guangxi Scientific Experimental Center of Traditional Chinese Medicine, Guangxi University of Chinese Medicine, Nanning 530200, China,Guangxi Key Laboratory of Efficacy Study on Chinese Materia Medica, Nanning 530001, China;Guangxi Collaborative Innovation Center of Study on Functional Ingredients of Agricultural Residues, Nanning 530200, China;Guangxi Scientific Experimental Center of Traditional Chinese Medicine, Guangxi University of Chinese Medicine, Nanning 530200, China,Guangxi Key Laboratory of Efficacy Study on Chinese Materia Medica, Nanning 530001, China;Guangxi Collaborative Innovation Center of Study on Functional Ingredients of Agricultural Residues, Nanning 530200, China;Guangxi Scientific Experimental Center of Traditional Chinese Medicine, Guangxi University of Chinese Medicine, Nanning 530200, China,Guangxi Key Laboratory of Efficacy Study on Chinese Materia Medica, Nanning 530001, China;Guangxi Collaborative Innovation Center of Study on Functional Ingredients of Agricultural Residues, Nanning 530200, China;Guangxi Scientific Experimental Center of Traditional Chinese Medicine, Guangxi University of Chinese Medicine, Nanning 530200, China,Faculty of Pharmacy, Guangxi University of Chinese Medicine, Nanning 530200, China;Guangxi Key Laboratory of Efficacy Study on Chinese Materia Medica, Nanning 530001, China;Guangxi Collaborative Innovation Center of Study on Functional Ingredients of Agricultural Residues, Nanning 530200, China;Guangxi Scientific Experimental Center of Traditional Chinese Medicine, Guangxi University of Chinese Medicine, Nanning 530200, China,Guangxi Key Laboratory of Efficacy Study on Chinese Materia Medica, Nanning 530001, China;Guangxi Collaborative Innovation Center of Study on Functional Ingredients of Agricultural Residues, Nanning 530200, China;Guangxi Scientific Experimental Center of Traditional Chinese Medicine, Guangxi University of Chinese Medicine, Nanning 530200, China |
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| Abstract: | Kandelia candel belongs to the genus Kandelia of Rhizophoraceae. It is a kind of Marine plant growing in the coastal area and used as medicine by the people in the coastal area of Guangxi. Its chemical constituents mainly include flavonoids, terpenoids, phenolic acids, organic acids, sterols, nitrogenous compounds, polysaccharides and so on. Modern pharmacological studies have shown that Kandelia candel has many pharmacological activities, such as anti-tumor, bacteriostasis, anti-oxidation, lowering blood glucose and blood lipid, and anti-inflammatory. In this paper, the research status of the chemical constituents and pharmacological activities of Kandelia candel was summarized in depth, so as to provide reference for the clinical application, quality control and product development of this Marine traditional Chinese medicine. |
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| Keywords: | Kandelia candel Flavonoids Terpenoids Phenolic acids Tannins Antitumor activity Antioxidant activity Bacteriostatic activity |
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