隔姜灸联合瑞舒伐他汀治疗脾虚湿阻型肥胖并发高脂血症的临床观察＊

目的 观察隔姜灸联合瑞舒伐他汀对脾虚湿阻型肥胖并发高脂血症患者的临床疗效;方法 纳入60例脾虚湿阻型肥胖并发高脂血症的患者,按随机数字表法将其随机分为对照组和治疗组各30例,对照组采用运动疗法,饮食干预联合瑞舒伐他汀口服,治疗组在对照组的基础上施以隔姜灸治疗,观察两组患者的肥胖指标,脂质指标,血清脂肪因子及中医证候,并计算两组的有效率。结果 对照组患者的减肥总有效率为86.7%,降脂总有效率为80%,治疗组患者的减肥总有效率为100%,降脂总有效率为96.7%,两组患者在治疗后其肥胖指标,脂质指标,脂肪因子及中医证候均较治疗前有显著改善（P<0.05）,而治疗组较对照组改善更加明显（P<0.05）。结论 隔姜灸联合瑞舒伐他汀对脾虚湿阻型肥胖并发高血脂症具有很好的疗效,在改善患者肥胖程度和血脂异常的同时,也会改善患者体内的免疫状态及糖脂代谢紊乱。

Clinical Observation of Ginger Moxibustion Combined with Rosuvastatin in the Treatment of Spleen-Deficiency Dampness-Blocking Obesity Combined with Hyperlipidemia

Objective To evaluate the clinical effect of ginger moxibustion therapy in combination with rosuvastatin in obese patients with spleen-deficiency dampness and hyperlipidemia.Methods Data were evaluated in 60 obese patients with spleen-deficiency dampness and hyperlipidemia randomly assigned to two groups of 30 subjects. In both control and treatment groups, patients were prescribed rosuvastatin alongside an exercise and dietary intervention. In the treatment group, patients additionally underwent 3 courses of ginger moxibustion therapy. Obesity index, lipid indexes, adipocyte factor and TCM syndromes were assessed.Results In the control group, 86.7% of patients experienced weight loss, and 80% of patients saw a decrease in fat mass. In the treatment group, 100% of patients experienced weight loss, and 96.7% of patients saw a decrease in fat mass. After treatment, the obesity index, lipid index, adipocyte factor and TCM syndrome in both groups significantly improved when compared with data collected prior to treatment (P < 0.05); however, this improvement was more obvious in the treatment group than in the control group (P < 0.05).Conclusion Ginger moxibustion combined with rosuvastatin has a notable effect on spleen-deficiency dampness obesity with hyperlipidemia. This approach has not only been shown to improve markers associated with obesity and dyslipidemia but also benefit the immune status of patients suffering glucolipid metabolic dysfunction.