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增生消胶囊对大鼠慢性萎缩性胃炎的防治作用研究
引用本文:裴林,李佃贵,蔡春江,扈国杰,李振彬.增生消胶囊对大鼠慢性萎缩性胃炎的防治作用研究[J].中成药,2003,25(7):567-569.
作者姓名:裴林  李佃贵  蔡春江  扈国杰  李振彬
作者单位:1. 河北医科大学中医药研究院,石家庄,050031
2. 河北医科大学,石家庄,050011
3. 白求恩国际和平医院,石家庄,050071
基金项目:河北省科学技术厅科学技术研究与发展项目 :( 990 2 0 4)
摘    要:目的:观察增生消胶囊对大鼠慢性萎缩性胃炎的防治作用,探讨其作用机理。方法:采用主动免疫加胆汁、热水灌胃的综合方法模型、醋酸扭体法。结果:增生消胶囊可改善胃粘膜血流量,提高pH值抑制炎细胞浸润、腺体萎缩和不典型增生,并有明显的镇痛作用,无明显毒副作用。结论:增生消胶囊对大鼠慢性萎缩性胃炎具有较好的防治作用。

关 键 词:增生消胶囊  大鼠  慢性萎缩性胃炎  中医药治疗
文章编号:1001-1528(2003)07-0567-03
修稿时间:2002年10月31

Effects of prevention and treatment on atrophic gastritis in rats with Zengshengxiao Capsules
PEI Lin,LI Dian-gui,CAI Chun-jiang,HU Guo-jie,LI Zhen-bin.Effects of prevention and treatment on atrophic gastritis in rats with Zengshengxiao Capsules[J].Chinese Traditional Patent Medicine,2003,25(7):567-569.
Authors:PEI Lin  LI Dian-gui  CAI Chun-jiang  HU Guo-jie  LI Zhen-bin
Affiliation:PEI Lin1,LI Dian-gui2,CAI Chun-jiang2,HU Guo-jie2,LI Zhen-bin3
Abstract:Objective:To study the protective and therapeutic effects of Zengshengxiao Capsules (ZSX) on atrophic gastritis in rats. Methods: The model was established by methods of active immunity and gastrogavage with bile and hot water. The method of acetic acid writhing was used. Results: (ZSX) had actions of promoting the blood flow of gastric mucosa, increasing in pH, inhibiting inflammatory cell infiltration, glandular atrophia and atypical hyperplasia. It also had action of alleviating pain. There were no toxic and side effects. Conclusion: (ZSX) had remarkably preventive and therapeutic effects on atrophic gastritis of rats.
Keywords:Zengshengxiao Capsules  rat  atrophic gastritis  TCM treatment
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