| 中药鬼臼毒性成分HPLC/UV指纹图谱分析方法研究及与威灵仙、龙胆HPLC图谱比较 |
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| 引用本文： | 粟晓黎,林瑞超,王兆基,徐树棋,关锡耀.中药鬼臼毒性成分HPLC/UV指纹图谱分析方法研究及与威灵仙、龙胆HPLC图谱比较[J].中成药,2000,22(12):819-824. |
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| 作者姓名： | 粟晓黎 林瑞超 王兆基 徐树棋 关锡耀 |
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| 作者单位： | 1. 中国药品生物制品检定所,北京,100050
2. 香港特别行政区政府化验所,香港,九龙 |
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| 摘 要： | 目的：建立一个快速鉴别区分鬼臼、龙胆、威灵仙的分析方法。方法：以鬼臼所含毒成分为分析对象，选择适宜的ＨＰＬＣ条件，建立了指纹图谱分析方法，并对该方法进行了考察。结果：方法学考察结果表明，本研究建立的分析方法有较好重现性与复现性；鬼臼指纹图谱与威灵仙、龙胆ＨＰＬＣ图谱截然不同。结论：ＨＰＬＣ指纹图谱分析法可简便快速地鉴别区分鬼臼（桃儿七）、龙胆、威灵仙，并可用于不同来源鬼臼的鉴别。
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| 关 键 词： | 鬼臼 毒性成分 指纹图谱 威灵仙 龙胆 中药 鉴别 |
| 文章编号： | 1001-1528(2000)12-0819-06 |
| 修稿时间： | 2000年2月15日 |
Identification of Podophyllum Species and Radix Clematis and Radix Gentiana by HPLC/UV Fingerprint Analysis |
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| SU Xiao-li,LIN Rui-chao,WANG Zhao-ji,XU Shu-gi,GUAN Xi-yao.Identification of Podophyllum Species and Radix Clematis and Radix Gentiana by HPLC/UV Fingerprint Analysis[J].Chinese Traditional Patent Medicine,2000,22(12):819-824. |
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| Authors: | SU Xiao-li LIN Rui-chao WANG Zhao-ji XU Shu-gi GUAN Xi-yao |
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| Abstract: | Objective: To establish a method for indentification of the podophyllum emodi species, Radix Clematis and Radix Gentiana species. Methods: HPLC/UV fingerprint analysis method of toxic ingredient podophyllotoxin and its derivatives were developed, and the method had been evaluated. Results: The methodological evaluation showed that this method had a good repeatability and reproducibility, and different samples had different HPLC fingerprints. Conclusion: This method can be used to differentiate podophyllum emodi from two commonly used medicinal herbs of a different genus but having similar appearance, Radix Clematis and Radix Gentiana. |
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| Keywords: | podophyllum toxic ingredient HPLC fingerprint Radix Clematis Radix Gentiana |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
