舒胃汤联合复方消化酶胶囊治疗肝胃不和型功能性消化不良临床效果观察

目的:探讨分析舒胃汤联合复方消化酶治疗肝胃不和型功能性消化不良(Functional Dyspepsia,FD)的临床效果。方法:选取2016年2月-2019年2月收治的108例肝胃不和型功能性消化不良患者随机分为观察组和对照组,观察组给予舒胃汤联合复方消化酶胶囊治疗,对照组给予复方消化酶胶囊治疗,比较两组临床疗效,治疗前后中医症状评分、胃功能指标。结果:观察组临床疗效总有效率为94.44%较对照组显著提高(P<0.05),治疗前两组中医症状评分无统计学差异(P>0.05),治疗后两组早饱、上腹灼烧感、餐后饱胀不适、上腹痛评分均显著下降,且治疗后观察组早饱、上腹灼烧感、餐后饱胀不适、上腹痛评分下降更显著(P<0.05),治疗前两组胃功能指标无统计学差异(P>0.05),治疗后两组胃排空、胃动素、胃泌素指标水平均显著提高,且治疗后观察组胃排空、胃动素、胃泌素指标水平改善更显著(P < 0.05),观察组不良反应发生率为5.56%,较对照组显著性降低(P < 0.05)。结论:舒胃汤联合复方消化酶胶囊治疗肝胃不和型功能性消化不良可显著提高临床疗效,改善患者临床症状,促进胃功能提高,降低不良反应发生率,值得应用。

Observation on treating functional dyspepsia of the Ganwei Buhe type with the Shuwei decoction plus compound digestive enzyme capsules

Objective:To analyze the clinical effect of the Shuwei decoction(舒胃汤)plus compound digestive enzyme capsules on functional dyspepsia of the Ganwei Buhe type(肝胃不和型).Methods:108 cases were randomly divided into the observation group and control group.The control group was treated with compound digestive enzyme capsules,the observation group was treated with the Shuwei decoctionmore.The TCM symptom score and gastric function index before and after treatment and clinical efficacy in groups were compared.Results:The total efficiency in the observation group was significantly higher than that in the control group(P<0.05).There was no significant difference in the scores of TCM symptoms between the two groups before treatment(P﹥0.05).After treatment,the early satiety,upper abdomen burning sensation,postprandial fullness discomfort,upper abdominal pain scores were significantly decreased;those scores in the observation group were decreased more significantly(P<0.05).There was no significant difference in gastric function indexes between groups(P>0.05).After treatment,the levels of gastric emptying,motilin and gastrin were significantly increased in groups,and those levels in the observation group were observed better in the observation group(P<0.05).The incidence of adverse reactions in the observation group was,more significantly lower than the control group(P<0.05).Conclusion:The Shuwei decoction plus compound digestive enzyme capsules on FD of the Ganwei Buhe type can significantly improve the clinical efficacy and symptoms,promote the improvement of gastric function,reduce the incidence of adverse reactions,and is worthy of application.