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质量常数方法应用于山楂饮片等级评价研究
引用本文:石佳,章军,赵小亮,荆文光,刘静,张雪婷,刘安.质量常数方法应用于山楂饮片等级评价研究[J].中国现代中药,2022,24(1):128-133.
作者姓名:石佳  章军  赵小亮  荆文光  刘静  张雪婷  刘安
作者单位:1.中国食品药品检定研究院,北京 100050;2.中国中医科学院 中药研究所,北京 100700;3.中国中医科学院 医学实验中心,北京 100700
基金项目:国家自然科学基金项目( 81703945); 国家中医药管理局中药标准化项目( ZYBZH-Y-JX-27);北京市科委“十病十药”研发专项( Z171100001717029)
摘    要:目的:采用质量常数法对山楂饮片进行等级评价研究。方法:以不同产地、不同厂家的13批山楂饮片为研究对象,建立山楂饮片的质量常数,并用于山楂饮片的等级划分。结果:山楂饮片分为3个等级,一等品为质量评价结果在前20%的饮片,其质量常数(A)≥54.99,二等品为质量评价结果在20%~50%的饮片,其34.37≤A<54.99,其余为三等品,其A<4.37。结论:中药质量常数方法用于划分山楂饮片等级是可行的,能客观地反映不同等级山楂的质量。

关 键 词:质量常数  山楂  饮片等级  商品规格
收稿时间:2020/12/14 0:00:00

Grade Evaluation of Crataegi Fructus Pieces Based on Quality Constant Method
SHI Ji,ZHANG Jun,ZHAO Xiao-liang,JING Wen-guang,LIU Jing,ZHANG Xue-ting,LIU An.Grade Evaluation of Crataegi Fructus Pieces Based on Quality Constant Method[J].Modern Chinese Medicine,2022,24(1):128-133.
Authors:SHI Ji  ZHANG Jun  ZHAO Xiao-liang  JING Wen-guang  LIU Jing  ZHANG Xue-ting  LIU An
Affiliation:1.National Institutes for Food and Drug Control, Beijing 100050, China;2.Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China;3.Experimental Research Center, China Academy of Chinese Medical Sciences, Beijing 100700, China
Abstract:Objective:To evaluate the grade of Crataegi Fructus pieces with the quality constant method.Methods:Thirteen batches of Crataegi Fructus pieces from different producing areas and manufacturers were selected as the research object,and the quality constant was used for the classification of Crataegi Fructus pieces.Results:Crataegi Fructus pieces can be divided into three grades.GradeⅠincludes the decoction pieces with the top 20%quality evaluation results,whose quality constants are greater than or equal to 54.99.GradeⅡcorresponds to the decoction pieces with the quality evaluation results ranking 20%-50%,and their quality constants are smaller than 54.99 but greater than or equal to 34.37.The others constitute GradeⅢ,with the quality constant being smaller than 34.37.Conclusion:It is feasible to use the quality constant method of traditional Chinese medicine to grade Crataegi Fructus pieces,which can objectively reflect the quality of different grades of Crataegi Fructus.
Keywords:quality constant  Crataegi Fructus  grade of medicinal pieces  commodity specification
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